38


Chapter 2 Medication Use


The following drugs are included in the assessment of med- ication use (Tables 2.8 through 2.10 and Boxes 2.14 through 2.16, pages 38–51): • statins (Table 2.8)2 • nonstatin lipid-lowering agents (Box 2.14)2 • antihypertensive drug dosing (Table 2.9)5 • glucose-lowering medications for T2D (Box 2.15)4 • insulins (Table 2.10)12 • pharmacological treatment of obesity (Box 2.16)13


Table 2.8 High-, Moderate-, and Low-Intensity Statin Therapy2


Statin Therapy Agent (Brand Name)


Atorvastatin (Lipitor)


Rosuvastatin (Crestor)


Simvastatin (Zocor)


Pravastatin (Pravachol)


Lovastatin (Mevacor)


Fluvastatin, extended release (Lescol XL)


Fluvastatin (Lescol) Pitavastatin (Livalo)


average of ≥ 50%. b


Daily Dose High-


Intensitya 40–80 mg


20 (40) mg


NA NA


NA NA NA NA


Moderate- Intensityb


10 (20)mg (5) 10 mg


20–40 mg 40 (80) mg


40 mg Low-


Intensityc NA


NA 10 mg 10–20 mg 20 mg 80 mg 20–40 mg 40 mg


twice daily 2–4 mg


NA 1 mg


a Daily dose decreases low-density lipoprotein cholesterol (LDL-C) levels by an Daily dose decreases LDL-C levels by an average of 30% to < 50%.


c Daily dose decreases LDL-C levels by average of < 30%.


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