20


Chapter 2


Box 2.1 Treatment of Cholesterol to Reduce Atherosclerotic Disease Riska


Group 1 • Individuals with clinical atherosclerotic cardiovascular disease (ASCVD)


Group 2 • Individuals with primary elevations of low-density lipoprotein cholesterol (LDL-C) concentration ≥ 190 mg/dL


Group 3


• Individuals 40–75 years with diabetes and LDL-C concentra- tion 70–189 mg/dL


• Individuals of all ages with diabetes and overt cardiovascu- lar disease (CVD); high-intensity statin therapy recommended


• Individuals age < 40 and with diabetes and additional CVD risk factors; consider using moderate- or high-intensity sta- tin therapy


• Individuals age > 75 with diabetes and without additional CVD risk factors; consider using moderate-intensity statin therapy; for clients with additional CVD risk factors, consider using high-intensity satin therapy


Group 4


• Individuals without clinical ASCVD or diabetes age 40–75 with LDL-C levels 70–189 mg/dL and an estimated 10-year ASCVD risk of 7.5% or higher


a This treatment is for client groups that benefit from statin therapy in addition


to lifestyle therapy from the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol.2


Box 2.2 Classification of Cholesterol and Triglyceride Lev- els from the National Lipid Association3


Non-HDL-C (mg/dL)a < 130


Desirable


130–159 Above desirable 160–189 Borderline high 190–219 High ≥ 220


Very high Continued on next page.


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