marijuana dialogue would change from one of denial to one of precaution. Te message is not that marijuana is the scourge of the planet, nor is it a panacea for all ailments. It fits perfectly in the risk/benefit paradigm of other drugs.
References 1
Laurence Steinberg. A social neuroscience perspective on adolescent risk-taking. Developmental review Vol. 8, Issue 1, March 2008, pages 78–106.
2
“Pleasure Unwoven” (2009) Addiction-Dr. Kevin McCauley, the Institute for Addiction Study
3
Pierce, Christopher The mesolimbic dopamine system: The final common pathway for the reinforcing effect of drugs of abuse? Neuroscience & Biobehavorial Reviews. Volume 30, 2006, pages 215–238.
4
Meir, MH. et al (2012) Persistent cannabis users show neuropsychological decline from childhood to midlife. Proc. National Academy of Science USA 109 E2657–E2662).
5
Weiland, Barbara, et. al. Daily Marijuana Use is Not Associated with Brain Morphometric Measures in Adolescents or Adults. The Journal of Neuroscience. 28 Jan. 2015, 35(4). 1505–1512).
11 10
6
NIH 2014 Monitoring the Future. DrugFacts: High School and Youth Trends.
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Gallily, Ruth, et al Overcoming the Bell-shaped Dose- Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol. Pharmacology and Pharmacy Review, 2015,6,75–85.
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Pertwee, Roger G. Cannabinoid Receptor Ligands. Tocris Biosciemce Review. 2013.
9
Chiara, GD. Drug addiction as a dopamine-dependent associative learning disorder. European Journal of Pharmacology Vo. 376 issues 1–3, June 1999, pages 13–30.
Pierce, Christopher R., Kumaresan, Vidhya. The mesolimbic dopamine system: The final common pathway for the reinforcing effect of drugs of abuse? A Review, Vol. 30, Issue 2, 2006. Pages 215–238.
Anthony et al Comparative Prevalence of dependence among different drugs. Exp. Clin. Psychopharmacology 2(3),1994 Pages 244–268.
12
Olds, J. Pleasure centers of the brain. Scientfic American 1956;195:105–16.
13
Bostwick, Michael J. Blurred Boundaries: The Therapeutics and Politics of Medical Marijuana Clin Proc. 2012 Feb. 87(2): 172–186.
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Jacobus, J et al Functional Consequences of Marijuana Use in Adolescents. Pharmacol. Biochem. Behav. 2009 June:92(4) 559–565.
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