ISCA Iscaguard® Iscaguard FPX ® Iscaguard® FPX is an optimised blend of paraben esters in


phenoxyethanol giving the advantages of broad-spectrum activity and ease of liquid handling.


Iscaguard® FPX is compatible with most personal care


ingredients and the presence of phenoxyethanol reduces, or overcomes the inactivation of parabens exhibited by some nonionic emulsifiers when parabens are used alone. In formulations with a high protein content, it may be necessary to use a higher concentration of Iscaguard® compared with a similar formulation with no protein present.


FPX


At typical use concentrations of 0.3 – 1.0%, Iscaguard®


membranes. Iscaguard®


FPX is non-irritant to skin, eyes and mucous


Staphylococcus aureus Bacillus cereus


FPX has application in all categories of


personal care products and retains its activity over the range pH 3 – 8.


Regulatory Status Iscaguard®


FPX is permitted for use in personal care


products in the European Union (maximum 1.39%), the USA (safe as used) and Japan (maximum 1.39%). INCI name: phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben.


Using Iscaguard® Iscaguard®


FPX FPX is soluble in water to approximately 0.5%,


but may be incorporated at higher concentrations into formulations containing surfactants, oils and waxes. Prolonged heating at elevated temperatures is not recommended, but Iscaguard®


FPX may be added immediately after emulsification in hot processes. Aspergillus niger 0.13 Enterococcus faecium Candida albicans Saccharomyces cerevisiae


0.21 0.21 0.21


0.12 0.11


Table 20 Antimicrobial activity of Iscaguard® Microorganism


Pseudomonas aeruginosa Escherichia coli Proteus vulgaris


FPX


Minimum inhibitory concentration (%)


0.32 0.24 0.24


Preservative Blends


Table 19 Solubility of Iscaguard® Water


Propylene glycol Butylene glycol


Isopropyl myristate


8


FPX (% w/w @ 25°C)


Approx. 0.5% Miscible Miscible Miscible


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