13 Iscaguard PPM ® Iscaguard® PPM is an optimised blend of methylparaben
and propylparaben in phenoxyethanol giving the advantages of broad-spectrum activity and ease of liquid handling.
Iscaguard® PPM is compatible with most personal care
ingredients and the presence of phenoxyethanol reduces, or overcomes the inactivation of parabens exhibited by some nonionic emulsifiers when parabens are used alone. In formulations with a high protein content, it may be necessary to use a higher concentration of Iscaguard®
PPM compared with a similar formulation with no protein present.
At typical use concentrations of 0.3 – 1.0%, Iscaguard®
membranes. Iscaguard®
PPM is non-irritant to skin, eyes and mucous PPM has application in all categories of
personal care products and retains its activity over the range pH 3 – 8.
Regulatory Status Iscaguard®
PPM is permitted for use in personal care
products in the European Union (maximum 1.39%), the USA (safe as used) and Japan (maximum 1.39%). INCI name: phenoxyethanol, methylparaben, propylparaben.
Using Iscaguard® Iscaguard®
PPM PPM is soluble in water at approximately
0.5%, but may be incorporated at higher concentrations into formulations containing surfactants, oils and waxes. Prolonged heating at elevated temperatures is not recommended, but Iscaguard®
PPM may be added immediately after emulsification in hot processes.
ISCA Iscaguard®
Preservative Blends
Table 29 Solubility of Iscaguard® Water
Propylene glycol Butylene glycol
Isopropyl myristate
Table 30 Antimicrobial activity of Iscaguard® Microorganism
Pseudomonas aeruginosa Escherichia coli Proteus vulgaris
Staphylococcus aureus Bacillus cereus
Enterococcus faecium Candida albicans Saccharomyces cerevisiae Aspergillus niger
PPM (% w/w @ 25°C)
Approx. 0.5% Miscible Miscible Miscible
PPM
Minimum inhibitory concentration (%)
0.35 0.26 0.27
0.29 0.22 0.32
0.16 0.12
0.15
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