Sweeteners
A 2023 observational study published in Nature Medicine found a link between using erythritol as an added sweetener and CVD events in people with heart disease.
With results like these, no wonder the latest advice from the World Health Organisation (WHO), issued in 2023, discourages the use of non-sugar sweeteners to control weight or reduce the risk of noncommunicable diseases. This recommendation is based on a systematic review of the available evidence, concluding that such sweeteners provide no long-term benefit in reducing body fat in adults or children, and that long-term use may increase the risk of Type 2 diabetes and CVD. Yet controversy persists. Dr Kimber Stanhope, a research nutritional biologist at the University of California, Davis, has researched sugar and many types of LCS intensely, notably sugar alcohol erythritol. She remains unconvinced by many of the popular arguments. She has never seen human intervention data showing that aspartame has negative effects. ”I don’t mean population data, which shows a positive association between use of non-caloric sweeteners and CVD, diabetes and obesity – likely because people with CVD, diabetes and obesity have been instructed to reduce their sugar intake and non- caloric sweeteners help them do that,” she explains. “To know if non-caloric sweeteners cause increased risks, we need to look at dietary intervention studies. Those studies have yet to find any negative effects of aspartame, and some have shown positive effects because it is replacing sugar and its calories.” Aspartame breaks down into two amino acids and a methyl group, all of which are produced in higher quantities by many foods. For instance, a 3oz piece of meat provides far higher levels of those amino acids than a 12oz soda containing aspartame. In short, you can drink several aspartame-sweetened sodas each day – and you’ll still have less of those amino acids than from a steak. Furthermore, bodies use those amino acids to build and replace proteins.
Ingredients Insight /
www.ingredients-insight.com
“You will also get fewer methyl groups from those sodas than you get from whole fruit, and whole fruit consumption is associated with a low risk of CVD, diabetes and obesity,” Stanhope adds. “Therefore, it is not plausible to me that the small amounts of amino acids and methyl groups in aspartame- sweetened soda can cause disease, but the higher amounts in meat and fruit do not.”
Ending the controversy?
As the debate over artificial sweeteners rumbles on, natural alternatives are emerging. One good example is sugar alcohols, which contain far fewer calories than sugar and break down slowly, in the gut. This helps prevent spikes in blood sugar and insulin levels.
“They are a good option for individuals with diabetes and are a healthier alternative to sugar because of their lower calorie content and reduced glycemic response,” notes Shapiro. “Nevertheless, when consumed in large amounts they can cause gastrointestinal problems such as abdominal pain, bloating and diarrhoea.”
This can be explained by how sugar alcohols are digested. Because the process happens slowly they have more time to feed bacteria in the gut, which can produce excess gas – though individual differences in metabolism, gut microbiome composition and dietary habits all determine how people respond.
The possible long-term health risks of sugar alcohol are still being explored, but a 2023 observational study published in Nature Medicine found a link between using erythritol as an added sweetener and CVD events in people with heart disease, or who had risk factors such as diabetes and high blood pressure. Even so, Shapiro concedes that these findings have not been confirmed in subsequent studies.
$225.86m
The expected value of the global erythritol market in 2023, reaching around $449.6m by 2033.
Future Market Insights $375.5m
The worth of the global aspartame market in 2021, which is expected to grow to $561.7m by 2031.
Allied Market Research 63
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Shutterstock.com
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