Company insight
Plant-based solution for gut and overall health
Bionap is a dynamic vertically integrated company producing standardised botanical extracts, derived from plants and fruits surrounding Mount Etna, the major volcano in the Mediterranean area. It is based in Italy and since 1997 has followed circular economy processes with the aim of helping regenerate the Earth’s natural resources.
ionap is a cutting-edge player in manufacturing ingredients for health and well-being, personal care, and animal health markets. Our vision is: to spread the principles of the Mediterranean tradition for people’s well- being, thanks to our cutting-edge scientific research applied to natural resources, in full respect of biodiversity.
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Bionap, always attentive to market needs relating to people’s health and well-being, has found that a healthy gut means healthy brain performance because they are connected to energy, better mood, stress management, brain health and social benefit. The gut health phytochemical and plant extract dietary supplements market is expected to grow from USD 5,936 million in 2023 to USD 11,601 million in 2030, with a CAGR of 10.05%. This market segment accounts for 12.4% of the global market in 2022, and the share is expected to increase further to 13.5% during the forecast period, to 2030. That’s why Bionap has developed ODILIA™, a powder extract obtained from Opuntia cladode juice standardised in polysaccharides and piscidic acid, a characterising fingerprint of this plant. Thanks to its composition, ODILIA™ acts as a prebiotic agent, supporting a healthy gut microbial population and may act indirectly on overall health such as immune and mucosal support and gut-brain and gut-muscle axis. The last clinical trial has demonstrated that the unique phytocomplex of polysaccharides and piscidic acid is able to have a positive impact on overall health: Supports healthy gut mucosal barrier Supports the gut homeostasis with a prebiotic activity
Supports the overall health Ingredients Insight /
www.ingredients-insight.com
Improves gut homeostasis The Firmicutes/Bacteroidetes ratio is a marker of gut health when it’s close to one (higher values are related to dysbiosis). Odilia was able to improve this ratio of about 35% and 43% after four and eight weeks of supplementation respectively getting closer to one;
Supports the healthy gut mucosal barrier The supplementation highlighted an increase in the Clostridium XIVa cluster which has protective microbiological activity and functions related to the mucosal barrier that regulates mucosal homeostasis by producing SCFAs and selectively attracting T-reg cells that secrete immunomodulatory cytokines;
Supports the overall health The supplementation led to a significant enrichment of beneficial microorganisms which are generally associated with immunomodulatory, anti-allergy, anti-oxidative and anti-inflammatory functions, as well as associated with cognition; ODILIA™ supplementation highlighted a depletion of pro-
inflammatory and potentially pathogenic taxa, leading to a more balanced intestinal microbial community. Moreover, there was an increase in bacterial species that produce short-chain fatty acids (SCFAs), which in turn, may influence brain-gut- muscle axis communication and brain function directly or indirectly, as well as the energy metabolism and the feeding behaviour as the stress-associated eating. The idea of the brain-gut-muscle axis is gradually being confirmed by growing scientific evidence that could also be described as overall health. The gut homeostasis seems a key factor in human health as the basis for a positive interaction of intestinal microbiota, central nervous system, skeletal muscle energy metabolism, and feeding behaviour regulation.
*These statements haven’t been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
www.bionap.com 31
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