6 Maximising yields in preparative LC
Accurate, real-time flow monitoring is now more accessible for chemists working at preparative scale, thanks to the Prep Flowmeter from Testa Analytical. Designed to handle flow rates of up to 650 ml/min, the instrument helps optimise compound recovery and enhance the efficiency of fraction collection.
In preparative liquid chromatography, fractions are typically collected based on volume. However, fluctuations or inaccuracies in flow rate can compromise both purity and yield. By continuously measuring absolute flow rates, the Prep Flowmeter enables tighter control of the separation process - improving both the quality and quantity of collected fractions.
Beyond process optimisation, the device is also a valuable tool for troubleshooting and routine performance validation of chromatography systems.
Compact and USB-powered, the Prep Flowmeter integrates easily into most setups. It employs a non-invasive thermal flow sensor that delivers high-resolution, high-sensitivity readings without interfering with the process stream. Its wide dynamic range makes it suitable for a variety of preparative applications.
Flow data can be monitored in real time using an intuitive PC-based app, which supports continuous recording and secure data storage. A bright OLED display shows the current flow rate locally, while onboard communication buffering ensures no data is lost - even if the PC connection is briefly interrupted. More information online:
ilmt.co/PL/bwyY
64897pr@reply-direct.com
Advanced chromatography columns for ADC characterisation
Phenomenex Inc, a global leader in separation science technologies, introduces Biozen™ Native RP-1 and RP-5 - innovative chromatography columns designed for the precise and efficient characterisation of Antibody-Drug Conjugates (ADCs). As ADCs become key players in targeted cancer therapies, these new columns enable reversed-phase separation under native conditions with direct online mass spectrometry (MS) detection.
Featuring proprietary RP-1 and RP-5 particle technology, the columns offer fast, robust native reversed-phase resolution of all Drug to Antibody Ratio (DAR) species, including positional isomers. This advanced design reduces run times and sample handling, delivering higher quality data more efficiently than traditional methods.
More information online:
ilmt.co/PL/DGM8 and
ilmt.co/PL/WwBn 64855pr@reply-direct.com
Advanced GC with CO2
reduction visualisation
Shimadzu has announced an important update for its compact Brevis GC-2050 gas chromatograph, adding a host of new features that significantly broaden its application scope. This latest development transforms the system into a fully equipped, flexible solution capable of supporting an even wider range of industries - with particular focus on the growing demands of the Green Transformation (GX) sector.
A standout addition is the introduction of the world’s first CO2 reduction visualisation function for a gas chromatograph. The system’s new ECO Idling Function learns usage patterns and automatically optimises operating schedules based on workload, activating energy-saving modes during idle periods. The integrated software not only cuts down on gas and electricity consumption but also displays tangible data on CO2
reductions and cost savings achieved, giving laboratories meaningful insights into their sustainability performance.
To meet the increasing need for precise and efficient gas analysis in areas such as green energy development and process control, Shimadzu has enhanced its Automatic Gas Analysis System. This now pairs an improved Thermal Conductivity Detector (TCD) with the Auto Gas Injector GI-30, delivering superior sensitivity in a compact format.
Further extending the system’s versatility, the Brevis GC-2050 can be configured with a range of compatible accessories. These include the Jetanizer/Polyarc microreactor system for sensitive, easy quantification using a universal FID detector, and a customised GC setup featuring the VB-30 Series valve box for petrochemical and gas manufacturing applications. Other options include the TD-30 thermal desorption system for precise atmospheric VOC analysis, the PY- 3030D pyrolysis furnace for resin and additive characterisation, and the HS-20 NX headspace sampler for analysing volatile compounds in both liquids and solids. Additionally, a multi-detector configuration can be assembled using Advanced Flow Technology for simultaneous compound detection.
Originally launched in 2023, the Brevis GC-2050 continues to build on Shimadzu’s reputation for compact, high-performance gas chromatography systems. These new enhancements enable laboratories to access a complete, modular GC platform designed to deliver precise results, reduce environmental impact, and save valuable bench space.
More information online:
ilmt.co/PL/lKej 64459pr@reply-direct.com
Customised HPLC storage cabinet with integrated waste management
The new Köttermann HPLC storage cabinet combines flexible storage for HPLC and UHPLC systems with a thoughtfully designed waste management solution. The spacious cabinet can be customised to suit the HPLC device model and local requirements. Whether free-standing or as part of a laboratory bench, each version can be adapted precisely to the room and equipment dimensions, thus optimising space utilisation.
A convenient pull-out in the lower cabinet section allows the HPLC system to be extended for easy service and maintenance. Technical interventions can thus be carried out in a time-saving and ergonomic manner without having to move or relocate the device.
Waste is collected cleanly and conveniently in a collector unit in the base cabinet section. A user-friendly sensor continuously monitors the fill level and signals when emptying is required. This ensures that solvent waste is stored safely within the cabinet - without additional space requirements or external equipment.
The modular Köttermann design allows for retrofitting at any time – _for example, pull-out shelves for solvent bottles, media connections or cable glands. The internal dimensions are precisely tailored to standard tower UHPLC devices. Built-in plug sockets and data sockets in the interior and storage space for a PC simplify ongoing operation. In addition, a point extraction system can be retrofitted to remove solvent vapours directly at the source.
More information online:
ilmt.co/PL/9M0B 64682pr@reply-direct.com
INTERNATIONAL LABMATE - SEPTEMBER 2025
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60
