Reagents, Reference Materials & Laboratory Chemicals


Fast-track neural cell production with iPSC differentiation kits


Quality reagents and custom solutions for molecular biology


Founded in 2002, Bioron GmbH specialises in high-quality molecular biology reagents, supplying a wide range of DNA, RNA products, and tailored solutions to support biotechnological research, diagnostics, and therapeutic development. The company has built a strong reputation for ethically sourced, highly pure human DNA products, including its fl agship Human Placenta DNA and COT I Human DNA.


AMSBIO has launched a comprehensive range of Quick- Neuron™ differentiation kits, designed to simplify and accelerate the generation of specific neural cell types from human induced pluripotent stem cells (iPSCs). These kits provide researchers with a fast, consistent, and animal-free approach to producing high-purity neurons - enabling more efficient disease modelling, drug screening, and regenerative medicine studies.


Each kit includes a streamlined, highly reproducible protocol that allows users to generate functional neural cell types within just 1–2 weeks. The easy-to-follow workflows are ideal for labs seeking standardisation without compromising cell quality or reproducibility. Importantly, the differentiation process avoids the use of animal-derived materials and leaves no genetic footprint, thanks to a proprietary non-integrating transcription factor- based method available in either Sendai virus or synthetic mRNA format.


For added convenience, AMSBIO also offers a range of pre-differentiated cell lines – both diseased and healthy controls – for each neuron type, allowing users to bypass the initial iPSC steps if desired.


The Quick-Neuron™ Excitatory Differentiation Kit produces high-purity glutamatergic neurons expressing key markers including TUBB3 and vGLUT1. These neurons exhibit typical neurite outgrowth, and electrophysiological analysis via patch clamp confirms spontaneous action potential generation.


The Dopaminergic Differentiation Kit enables rapid mRNA-driven production of dopaminergic neurons expressing TH and TUBB3. Likewise, the GABAergic Differentiation Kit delivers robust populations of inhibitory neurons within 10 days, validated by expression of appropriate markers and neuronal morphology. AMSBIO also supplies ready-made human iPSC-derived GABAergic neurons for immediate use.


Rounding out the collection, the Cholinergic Differentiation Kit allows for fast and efficient generation of cholinergic neurons expressing TUBB3 and ChAT, supporting applications in both neurodegenerative disease research and drug development.


All kits are based on human iPSCs made under licence from the California Institute for Regenerative Medicine (CIRM), providing quality and consistency aligned with translational research goals.


These versatile, scalable tools empower researchers working at the interface of neuroscience, genomics, and biotechnology to produce defined human neural cells quickly and reliably - all without relying on animal models.


More information online: ilmt.co/PL/6Rd0 65013pr@reply-direct.com


Antibody cocktails simplify EV staining and phenotyping


Biotium has launched its ExoBrite™ CD9/CD63/CD81 Antibody Cocktails, designed to simplify and enhance extracellular vesicle (EV) analysis by flow cytometry. These new cocktails target the three most commonly used EV markers - CD9, CD63, and CD81 - offering researchers bright, reliable staining with minimal optimisation.


Available in single-colour and 3-colour formats, the cocktails provide flexibility for different experimental needs. The single-colour version is ideal for high-coverage EV staining, offered in green, orange, or far-red. The 3-colour cocktail supports multi-marker phenotyping, available in blue/green/far-red or green/orange/far-red combinations, enabling streamlined EV profiling without compromising signal-to-noise quality.


Each antibody in the ExoBrite™ cocktails is optimised for bright, efficient staining, and the low-aggregation formulation reduces background and improves accuracy. By combining three antibodies in one mixture, researchers save both time and reagents while integrating seamlessly into existing flow cytometry workflows.


“Many researchers already stain all three tetraspanins simultaneously,” said Dr Alexis Madrid, head of Biotium’s EV product development group. “Our new cocktails simplify this process while maintaining high performance for EV phenotyping.”


ExoBrite™ cocktails are specifically validated for EV detection, unlike conventional antibodies, ensuring consistent tetraspanin profiling. They can be paired with ExoBrite™ True EV Membrane Stains or EV Surface Stains for multi-parameter analysis. For western blot applications, Biotium also offers fluorescent ExoBrite™ antibodies against CD9, CD63, and CD81 for sensitive detection in EV extracts.


More information online: ilmt.co/PL/QpLG 65525pr@reply-direct.com


Human Placenta DNA, derived from placental tissue, is widely used in chromosomal and whole genome analysis, FISH, Southern blotting, genomic library construction, and PCR-based assays. COT I Human DNA, enriched in repetitive sequences, is especially valuable for next-generation sequencing (NGS) and ensures high specifi city in diagnostic and genetic testing.


Bioron’s extensive product range also supports PCR technologies with enzymes, master mixes, reverse transcription kits, nucleotides, DNA ladders, and purifi cation kits. These products are designed to meet the rigorous standards of academic and commercial laboratories, delivering reliable, high-performance results for molecular diagnostics and research.


Committed to quality and regulatory compliance, Bioron maintains ISO 13485:2016 certifi cation and adheres to Good Manufacturing Practices (GMP), ensuring products meet international standards for clinical trials, diagnostic testing, and therapeutic applications.


Customer-focused from small-scale development to large orders, Bioron offers tailored product specifi cations, rigorous quality control, and personalised support. Their fl exibility and expertise make them a trusted partner in advancing biotechnology research and medical innovation.


With a comprehensive portfolio, regulatory rigor, and dedication to customer needs, Bioron GmbH continues to play a key role in providing essential molecular biology reagents and reference materials worldwide.


More information online: ilmt.co/PL/lQGO 64851pr@reply-direct.com


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