6 Enhanced Degassers for GPC Applications
Biotech Fluidics recently introduced two advanced degassers designed specifically for Gel Permeation Chromatography (GPC) applications. These degassers, known as the DEGASi Plus GPC and DEGASi Plus GPC Semi-Prep, are designed to deliver superior performance and efficiency.
In liquid chromatography systems, changes in pressure or temperature can cause gas molecules to form bubbles. This can have a negative impact on the precision, accuracy, and performance of the equipment. To mitigate this issue, using an online degasser is a reliable technique for removing dissolved gases from the fluid stream. These degassers have been proven to prevent bubble formation, reduce noise, and improve baseline stability, thereby ensuring more consistent results. However, some degassers are not suitable for GPC applications that use 100% organic solvents and may struggle to provide optimal performance in these conditions.
To address this issue, Biotech Fluidics has developed the DEGASi Plus GPC and DEGASi Plus GPC Semi-Prep, which are specifically designed to provide a solution to this challenge. These innovative high-performance degassers are suitable for use with all commonly used organic solvents, including hexane and chlorinated solvents, and are able to effectively remove dissolved gases by stenting the degasser membrane. This secure internal connection in the fluidic line is essential for efficient degassing in GPC and straight phase separations that use 100% organic solvents.
The DEGASi Plus GPC and DEGASi Plus GPC Semi-Prep are not only effective in removing dissolved gases, but they are also user-friendly and nearly silent during operation. These degassers require minimal bench space and are fully compatible with all commercial GPC/SEC systems. The DEGASi Plus GPC comes with 1-6 channels and utilises a continuous vacuum system monitoring to ensure optimal operational conditions are maintained. Additionally, Biotech Fluidics has included advanced error and leak checking functions, as well as their patented ZHCR®
control, to eliminate baseline
fluctuations, providing further innovative features as standard. With an exceptional chemical compatible flow path, this CE and RoHS compliant unit is built to operate seamlessly, even if run continuously (24/7) for more than 5 years. More information online:
ilmt.co/PL/EOBy
59805pr@reply-direct.com
Advanced Solution for Independent Digital Maintenance and Qualification of Chromatographic Systems
Regular maintenance of chromatographic systems is intended to ensure that the instruments operate at optimum efficiency and that the separation of substances meets the highest standards. However, the maintenance of chromatographs means a high financial outlay for many labs, as it is usually carried out by the equipment manufacturers. In addition to scheduling agreements, a lot of documents and data have to be exchanged between the user and manufacturer sides – resulting in confusing paperwork and organisational efforts.
In order to make maintenance more cost- and time-efficient, AnaTox GmbH & Co KG has added a new feature to its proven AIQ Tool. The qualification software now also allows a standardised maintenance procedure for all system components, which brings significant cost advantages for equipment maintenance. The software automatically recognises the components of the system and lists the corresponding maintenance steps and associated tests. The guided process subsequently reduces downtimes to a minimum. The condition before and after maintenance is clearly documented and digitally stored. With the AIQ Tool, laboratories see themselves in a position to maintain and qualify their chromatographic environment independently and vendor-independently via a single software.
An additional advantage of the tool is the reading of the chromatograph wear counters. This data helps customers track how often the equipment has been used and how heavily certain components have been stressed. Likewise, the implemented tests can also be used individually for fault diagnosis. In this way, it is possible to order and stock spare parts in a timely manner and at a lower cost, so that replacement can be carried out quickly without having to wait a long time for a technician.
More information online:
ilmt.co/PL/EOjG 59843pr@reply-direct.com
Adsorbable Organically Bound Halogens Analysis as per new DIN 38409-59
DIN has published method 38409-59 describing the determination of adsorbable organically bound halogens by combustion ion chromatography (CIC) in different water samples. AOX and AOF analysis according to the new standard is performed in two steps, preconcentration of the adsorbable organic halogens on activated carbon, followed by direct combustion and subsequent ion chromatographic (CIC) analysis. Metrohm’s blog article describes the new method and its application for the analysis of AOF, which provides a fast and economical solution for non-targeted PFASs screening.
Organohalogen compounds are widespread, persistent, and potentially toxic for humans and the environment. However, the techniques commonly used to monitor adsorbable organic halogens (AOX) can only determine the sum of organically bound chlorine, bromine, and iodine. These techniques do not provide individual results for AOCl, AOBr, and AOI, respectively, nor on the organofluorine (AOF) content.
DIN method 38409-59 describes a validated method for comprehensive AOX analysis including AOF by CIC. Analysis by CIC allows the determination of the sum parameter as well as the individual concentrations of adsorbable organically bound fluorine, chlorine, bromine, and iodine in different waters.
Advantages of the new standard method: selective determination of AOF, AOCl, AOBr, and AOI in waters; AOF as fast non-targeted screening for PFASs; efficient and low-maintenance AOX determination; easy-to-use, robust, and efficient.
Further details about the application can be found in the following Application Note and White Paper: Application Note AN-CIC-033 – Monitoring PFASs in water sources: Non-targeted adsorbable organic fluorine (AOF) analysis by CIC:
ilmt.co/PL/XAMQ White Paper WP-078 – Adsorbable organic fluorine (AOF) – a sum parameter for non-targeted screening of per- and polyfluorinated alkyl substances (PFASs) in waters:
ilmt.co/PL/8jVp More information online:
ilmt.co/PL/678b
59667pr@reply-direct.com
Automated Permeation Analysis Systems for EN 374
When handling dangerous chemicals, it is essential to wear protective clothing that has been tested to ensure it provides sufficient chemical protection. The level of protection is determined by testing the rate at which chemicals permeate through the material. For gloves to receive certification as ‘chemically protective’ by EN ISO 374-1, they must meet specific breakthrough times against several challenge chemicals.
Ellutia has developed an automated system for analysing permeation breakthrough rates. The system includes up to 18 permeation cells and optional automated challenge chemical introduction to increase sample throughput and automation. The cells hold the challenge chemical to one side of the sample material and periodically sample the headspace from the other side to plot the permeation breakthrough. The cells can be operated in series or parallel depending on the test requirements. The Ellutia 200 Series GC then analyses the headspace from the cells, and custom software automatically plots the results in real-time.
Learn about Ellutia’s automated permeation breakthrough analysis system. More information online:
ilmt.co/PL/JQed
60038pr@reply-direct.com
INTERNATIONAL LABMATE - APRIL 2023
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