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New Benchtop 3D X-ray Microscope Introduced Bruker have announced the new SKYSCANTM
1273 benchtop 3D X-ray microscope based on micro-computed tomography (Micro-CT) technology.
The SKYSCAN 1273 sets a new standard for non-destructive testing (NDT) with benchtop instruments, providing a performance level previously only achieved by floor standing systems.
Samples with up to 500 mm length, 300 mm diameter, and a maximum weight of 20 kg can be investigated with powerful and precise positioning stages. The combination of a higher-energy X-ray source running at higher power (130 kV, 39 W) and a large format 6-megapixel flat-panel detector with ultimate sensitivity and speed provides excellent image quality in just a few seconds. The SKYSCAN 1273 produces 3D images of internal structures with high resolution based on a voxel size smaller than 3 µm.
The comprehensive software for straightforward data collection, advanced image analysis, and powerful visualisation makes the SKYSCAN 1273 an easy-to-use 3D X-ray microscope. Micro-CT with helical scanning for distortion-free data acquisition and artefact-free reconstruction algorithms provides images without blurring, even for planar structures in all directions.
For high-speed requirements, InstaReconâ, one of the world’s fastest CT reconstruction solutions, accelerates 3D imaging up to 100 times compared to traditional algorithms.
The SKYSCAN 1273 benchtop 3D X-ray microscope requires minimum lab space, is easy to use, and virtually maintenance-free to offer high system uptime with low cost of ownership.
Dr Geert Vanhoyland, the Bruker AXS Product Line Manager for 3D X-ray Microscopy, commented: “The SKYSCAN 1273 is a turnkey solution for non-destructive 3D imaging, covering a variety of industrial and scientific applications. This includes defect detection for casting, machining, and additive manufacturing, inspection of complex electro-mechanical assemblies, pharmaceutical packaging, advanced medical tools, geological drill cores, and non-ambient microscopy.”
Dr Kjell Laperre, the Bruker BioSpin Micro-CT Market Product & Applications Manager, added: “The SKYSCAN 1273 significantly extends the capabilities in preclinical imaging. Its large sample compartment combined with the higher-energy, higher-power X-ray source allows ex vivo imaging of larger and higher density samples in forensic, orthopedic, paleontological, and zoology applications.”
More information online:
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New Scientific CMOS Camera Introduced
With a new sensor designed from the ground-up, Hamamatsu Photonics have taken the strengths of EMCCD and sCMOS sensors to engineer the most advanced sCMOS camera available today; the new ORCA-Fusion scientific CMOS Camera.
In recent times, sCMOS cameras have developed into the dominant technology for imaging applications where high sensitivity and high speed are required, gradually replacing cameras based on older CCD or EMCCD technology. The disadvantage of sCMOS in comparison with previous sensor technologies has always been the uniformity of the sensor in terms of gain, offset, and readout noise. A broad distribution of readout noise limits the visual appearance and data quality of a camera, particularly in low-light conditions. Hamamatsu Photonics are already market leaders in using offset and gain correction to improve the uniformity of our sCMOS cameras; coupled with a new sensor specifically designed to limit noise distribution, the ORCA-Fusion takes this to the next level.
The new ORCA-Fusion, built from the sensor up, balances the complex nuances of camera features to provide beautiful images and robust data at all light levels, especially in tough low-light conditions.
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New Super Resolution Confocal Imaging System at ScopeM Announced
The Scientific Center for Optical and Electron Microscopy (ScopeM) is a central scientific technology platform of ETH Zurich providing resources and services in light and electron microscopy as well as direct access to state-of-the-art microscopy and sample preparation equipment. They have recently integrated the re-scan confocal module from
confocal.nl to their super resolution STORM microscope. With this combination, they have the possibility to perform a fast, high resolution confocal image followed by a super-resolution (based on localisation microscopy) image on the same region of interest in a specimen.
Dr Dorothea Pinotsi is a staff scientist specialising in single-molecule, super resolution and spectroscopy applications. “There is a wide range of life science projects where confocal microscopy is beneficial. We are an open, multi-user core facility which provides both high-end equipment and expertise. Our interest in the Re-scan Confocal Microscope (RCM) from
Confocal.nl stemmed from the fact that it is a novel type of confocal microscope not only using a camera-based detection scheme, but also offering high resolution, together with high Signal to Noise ratio which is generally challenging especially in dim specimens. We heard about RCM through scientific publications as well as presence in conferences. We use many complementary microscopies wide-field fluorescence, TIRF, confocal point scanning and spinning disk, super-resolution microscopes such as: OMX (for Structured Illumination Microscopy) STED (Stimulated Emission Depletion Microscopy) and STORM (for Single-molecule Localization Microscopy). We also use correlative electron microscopy and fluorescence imaging platforms.”
Working with
Confocal.nl was a positive experience for Dr Pinotsi. “As a ‘young’ spin-off company,
Confocal.nl is a dedicated team closely linked to academia. Communication was easily established. This has been beneficial not only for reporting of issues/problems or answering questions but also for exchanging suggestions and scientific ideas for experiments and possible product improvements. Before and during purchase, we were in direct contact with both the
Confocal.nl team and Nikon Switzerland. The latter offered a solution for installing the RCM as part of the entire STORM system.”
Speaking about the installation in Zurich,
Confocal.nl’s CEO, Peter Drent, said: “We worked with the ScopeM team and Nikon Switzerland to configure this advanced super resolution system. ETH is a most prestigious research organisation and we are thrilled to have them select one of our pioneering, high sensitivity confocal systems.”
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The KL 2500 LED from Schott is the performance leader of cold light sources in the KL series. Due to its high light output, the brightness is equivalent to a 250-watt halogen lamp, and with its special features it complies with advanced requirements in life science and industrial applications for both stereo microscopy and macroscopy.
The KL 2500 LED combines all advantages of LED light with the advantages of illumination through fibre optics. It enables the full flexibility to realise all common illumination techniques. Together with the KL 300 LED, the KL 1600 LED and the KL 1500 Halogen from Schott the cold light sources portfolio provides solutions to the wide scope of challenges in microscopy. A vast selection of accessories (ringlights, goosenecks, filters) further enhances the performance. Schott is an international technology group with more than 130 years of experience in optical products.
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LED Cold Light Source Provides Solutions to Microscopy Challenges
INTERNATIONAL LABMATE - APRIL 2019
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