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18 New Ultra High-Performance Liquid Chromatograph Series Combines Intelligence and Efficiency


Shimadzu announces the release of the Nexera Ultra High-Performance Liquid Chromatograph series, incorporating artificial intelligence as Analytical Intelligence, allowing systems to detect and resolve issues automatically. The Nexera series makes lab management simple by integrating IoT and device networking, enabling users to easily review instrument status, optimise resource allocation, and achieve higher throughput.


The Nexera UHPLC series maximises reliability and uptime with fully unattended workflows that span from startup to shut-down. Operators can set the Nexera to start up at a specified time, so that it can complete auto-purge, equilibration, baseline checks and system suitability in advance, and be ready for analysis before they arrive at the lab. In addition, FlowPilot ramps up the flow rate gradually, reducing the possibility of damage to columns. The Nexera also has auto-diagnostics and auto-recovery capabilities that allow it to monitor pressure fluctuations to check for anomalies.


With remote mobile phase monitoring and integrated consumables management, the system maximises uptime and reliability. Real-time monitoring of mobile phase levels allows lab personnel to efficiently run batches and respond accordingly if there isn’t enough mobile phase before starting a run. In addition, Nexera tracks consumable usage and sends alerts when parts need replacing, allowing users to keep the system running at peak performance. The Nexera UHPLC series allows analysts to confirm parameters and monitor chromatograms in real time directly from a web browser on their smart device.


The Nexera UHPLC increases efficiency by automating workflows and maximising throughput analysis. The SIL-40 autosampler can process the entire injection cycle time in as little as seven seconds, and continuous analysis can be carried out on up to 44 MTPs (using 3 plate changers). The SIL-40’s plate changers enable non-stop temperature-controlled analysis of thousands of samples. The Nexera automatically blends mobile phases at any set ratio, which speeds up the preparation of buffer solutions and the dilution of solvents. Because it prepares the exact amounts required for analysis, the Nexera reduces waste and labour.


The Nexera’s elegant, compact design saves valuable bench space. Because it uses over 80% less electricity when on standby, it significantly reduces running costs and supports an environmentally-friendly lab.


More information online: ilmt.co/PL/ALxq 48661pr@reply-direct.com


Solution for Nitrosamine Testing in Children’s Rubber Based Products


Ellutia has developed an analysis solution, for the detection of carcinogenic and mutagenic Nitrosamines found in rubber products. The method utilises GC separation followed by an Ellutia 810 TEA (Thermal Energy Analyser) for detection. A specific focus on exposure to babies and young children falls under the scope of UK methods BS EN 71-12:2016 (Safety of toys; N-nitrosamines and N-nitrosatable substances) and BS EN 12868:2017 (Child use and care articles – Method for determining the release of N-nitrosamines and N-nitrosatable substances from elastomer or rubber teats and soothers). The Ellutia TEA 800 series is an approved detector for analysing compounds by these methods.


Potentially any item containing nitrites/nitrates could contain nitrosamines and any process that uses secondary amines, where the manufacturing process results in an introduction of atmospheric nitrous oxide, could produce nitrosamines.


As the TEA is a Nitrogen specific detector, the very high sensitivity and selectivity for the compounds of interest is superior to other detectors. The Ellutia 800 series TEA has the ability to interface with most commonly available GC models.


More information online: ilmt.co/PL/64k9 47372pr@reply-direct.com


Compass Chromatography Data System


CompassCDS is SCION Instruments’ universal chromatography data system designed for instrument control, data acquisition, processing and reporting. With its unique capacity for customisation, CompassCDS provides users with a powerful data analysis tool with extensive calibration and calculation options. Originating from the legacy Galaxie CDS, CompassCDS has evolved into the next generation CDS which easily integrates with LIMS, SCADA and other commonly used data management systems.


CompassCDS can either be installed as a simple, single PC workstation application controlling a couple of instruments, or as a fully scalable multi-lab, multi-instrument networked enterprise client-server solution, or anything in between.


The CompassCDS operator-friendly graphical user interface (GUI) has been designed to improve the operator experience by streamlining workflows, thereby increasing sample throughput and overall productivity. The dual view function, when used in conjunction with the InstantView option, enables users to run samples, view live data acquisition and review and report results from a single screen without the need to retrieve any data files. CompassCDS also comes standard with the feature set required to support laboratories that are required to comply with 21 CFR Part 11.


CompassCDS provides users with one of the most powerful chromatography data management solutions available today. However, there are often application specific instances that require additional flexibility and for these, Compass CDS has a comprehensive and well-documented API that enables the development of custom pre- and post-run plug-ins.


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2019 Chromatography Training Calendar Now Available


Improve your chromatography skills and meet your training requirements by attending courses provided by Hichrom. Courses are tailored to cater to every level of experience and provide knowledge you can use to immediately implement efficiencies and make improvements in your laboratory. Furthermore, training can be delivered at your site for your convenience.


Courses for 2019 include HPLC Method Development, HPLC Troubleshooting, and, new for 2019, Pharmaceutical Dissolution Testing and Ion Chromatography, in addition to the ever-popular Stepwise Introduction to Chromatography. Seminars are delivered by world renowned experts, including Mel Euerby and Mark Powell, as well as Hichrom’s own Technical Specialists. Whatever your requirements, Hichrom are sure to have a course suited to your interests.


Hichrom training courses provide valuable opportunities to refresh, update, and improve your chromatography skills, as well as network with other chromatographers.


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INTERNATIONAL LABMATE - APRIL 2019


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