Environmental Analysis 39
Fast Scan Time and Zero Cross-Talk on SCION TQ
Mass Spectrometer The triple quadrupole mass spectrometer (TQ MS) is rapidly becoming the instrument of choice for compound analysis in complex matrices because of its selectivity in multiple reaction monitoring (MRM) mode and the ability to simultaneously monitor multiple target compounds, even when their retention time windows are significantly overlapped.
A significant problem linked to shorter scan times for multiple MRMs is that of “cross-talk” and overall decrease in sensitivity. Where there are two MRMs with the same m/z fragment ions from different precursor ions and with short scan time, the collision cell (Q2) does not have enough time to clear the fragment ion (scan event) from the first MRM before a second MRM fragmentation takes place. The result is the product ion from the first MRM appears in the second MRM chromatogram as a “ghost peak” or artifact and thus confuses the chromatogram of the next transition. Cross-talk can be particularly problematic if the first MRM is of high intensity, as it can lead to increasingly plausible false positives on the subsequent MRM.
Reader Reply Card No. 170 Bruker Celebrates Double
Award Win at Pittcon 2012 The new GC-MS platform from Bruker Chemical and Applied Markets (CAM) Division – SCION TQ™ – picked up two prestigious awards at last week’s Pittcon in Orlando, Florida.
First up was the presentation of the 4th Annual Reader’s Choice Award for Gas Chromatography Products, sponsored by Laboratory Equipment Magazine.
Hot on the heels of this success, came the news that SCION TQ was the recipient of the 2012 Pittcon Editors’ Silver Award, given for the best new products at the 2012 Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy. Established in 1996, these independent awards, which represent the results of a poll of leading editors, have become an important feature of the world’s largest trade show for the laboratory equipment industry.
The SCION TQ and SCION SQ represent the first new-generation GC-MS products following Bruker’s acquisition in 2010 of the Varian Lab GC, GC-MS quadrupole, and ICP-MS products. Design innovations such as Axial-Flow ion source, heated auto-focusing q0 ion optics, and EDR off-axis detector ensure the lowest possible detection limits and longest operation times. The ultra-fast 180° curved collision cell of SCION TQ delivers a space-saving design, which reduces instrument footprint, thereby allowing laboratories to adopt triple quadrupole technology without sacrificing precious bench space. Introduced in July 2011, the SCION TQ and SQ have already seen great acceptance in markets around the world.
Reader Reply Card No. 169
Industries First Lens-Free
Triple Quadrupole MS In conventional Mass Spectrometry, lenses are required to focus and redirect the ion beam to maintain maximum sensitivity and resolution. In ideal MS there would be no requirement for lenses at all because of ion losses involved. A first for the MS industry is the SCION SQ and TQ patented “lens-free” technology from Bruker, which maintains a tightly focused ion beam without need for additional lenses. The problem with lenses is that they need to be tuned, retuned, cleaned and charged to maintain optimal system performance. Bruker’s lens-free technology offers a number of benefits including:
• reduced or non-existent downtime for maintenance
• no additional power required to control the lenses
• improvement in overall productivity
• enhanced robustness and sensitivity
Reader Reply Card No. 171
Food Testing Environmental Forensics QA/QC
Bruker’s Superior
SCION Compound Based Scanning Software Simplifies Multi-Residue Analysis
with GC-MS/MS Designed as ‘the gas chromatographers’ GC-MS system, Bruker’s double award winning SCION TQ™ GC-MS/MS promotes ease of use and increased workflow in busy analytical laboratories. The advantages offered by hardware innovations – reducing the instrument footprint by half but at the same time improving performance over traditional gas chromatography systems – are supplemented by the utility and ease of use of the unique SCION Compound Based Scanning (CBS) software. Bruker’s software for the SCION TQ includes a number of important tools and features to make method set-up, data analysis and comparisons of similar spectra much easier. With gas chromatographers in mind, the SCION software package includes: a CBS Multiple Reaction Monitoring (MRM) compound library for easy set up of methods; additional spectral libraries; plug in to multiple user-customizable spectral libraries with automatic search functions; and Bruker’s mass spectrometry (MS) workstation software.
Reader Reply Card No. 172
She’s smiling because it’s sweet. You’re smiling because you know it’s pesticide free and you chose the SCION TQ GCMS triple quad system from Bruker to make sure.
You‘re smiling because the system was so sensitive providing detection limits 10-100 times lower than the required regulation. You‘re smiling because Bruker Innovation made implementation so easy. Key innovations like Compound Based Scanning (CBS),; “lens-free“ elliptical ion-path providing ultra-high sensitivity and noise reduction with less tuning and maintenance; Axial ion source for robust performance with the toughest samples set SCION TQ apart from the rest. Whether your application is in food testing, environmental analysis, forensic/toxicology, sports doping SCION TQ will exceed your expectations and put a smile on your face
Bruker designs analytical solutions based around the needs of your key applications. Ask your nearest Bruker sales representative about how SCION GC-MS systems can help deliver unmatched productivity in your laboratory.
Visit
www.scionhasarrived.com for more information. Innovation with Integrity Reader Reply Card No. 173 GAS CHROMATOGRAPHY
Your Choice
For Real Innovation in Gas Chromatography
www.envirotech-online.com IET March / April 2012
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