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High Concentration Low Volume Zeta Potential Measurement The new ZEN1010 high concentration zeta potential cell for the market leading Zetasizer Nano particle


characterisation system from Malvern Instruments enables measurement in samples of up to 40% w/v. The design, which incorporates a reduced optical path length, can typically provide three times the concentration measurement ability of standard cells for a particular sample. Suitable for measurement in aqueous media, the new cell takes just 150µl sample in the measurement area. As a consequence of the


reduced optical path and reduced measurement volume area, there is less heat generation than in conventional cells making the ZEN1010 highly suitable for delicate samples, including biological materials such as proteins.


Although it operates just like a standard cell on the Zetasizer Nano, the ZEN1010 allows robust zeta potential measurements in highly concentrated samples. By requiring less sample dilution, it supports improved maintenance of the pH and chemical structure of the sample, for more directly relevant zeta potential measurement. This is especially important in many colloidal materials, where measuring the sample in its native state avoids the need for the often complicated centrifugation and dilution procedures needed to maintain sample integrity.


While the ZEN1010 is designed to offer the maximum concentration zeta potential measurement capability with a laser doppler electrophoresis technique, it also offers optimum stability for lower concentration samples. Its minimal sample volume requirements and small capillary are also beneficial for measuring samples with high conductivity.


Compatible with the existing Zetasizer Nano system and accessory range, the reusable high concentration zeta potential cell is easy to use.


Circle no. 438


Integra has announced the completion of an international customer survey gauging current opinion as to the essential characteristics of a high quality pipetting aid.


Target-Enrichment System for Next-Generation Sequencing


Agilent Technologies, Inc and Applied Biosystems, have introduced the Agilent SureSelect Target Enrichment System, which is optimised for the SOLiD™ System, a next-generation advanced genomic analysis sequencing platform. As part of the agreement, the companies are co-marketing the SureSelect system, which is a unique research tool for efficiently re-sequencing specific regions of interest in the genome. The tool saves researchers tremendous amounts of time and expense, often enabling them to conduct studies that would otherwise not be feasible.


In advance of the commercialisation, the SureSelect Target Enrichment System was made available to a number of research scientists using the SOLiD System on an early-access basis, including Dr John McPherson, Cancer Genomics director at the Ontario Institute for Cancer Research (OICR). Research scientists at OICR are using seven SOLiD Systems to identify genes critical to the development of cancer.


Agilent’s target-enrichment product line offers customer-specified mixtures of up to 55,000 biotinylated RNA probes, delivered in single tubes. The capture probes are 120 base pairs long, the longest currently on the market for this application. This makes them very effective at capturing DNA containing unknown mutations, such as single nucleotide polymorphisms, insertions or deletions. SureSelect products are packaged for a range of study sizes, from tens to thousands of samples, and are well suited for automation in very-high- throughput workflows, unlike other commercially available products for this application.


Users can design their own custom SureSelect mixtures using the Agilent eArray online design tool, which contains many key genomes and also lets users upload their own sequences. This intuitive, Web-based design tool is the heart of Agilent’s custom genomics product manufacturing capability and is now expanded to the new SureSelect platforms. eArray allows researchers to easily design the tools they need without up-front design fees.


Circle no. 439


Knowledge of customer needs is key to development of successful products. “We want to offer the best products on the market, so we decided to find out which pipettor features really matter by directly asking customers who had recently purchased a PIPETBOY,” said Fabrizio Baumann, Product Manager at Integra.


“The survey generated a lot of interesting feedback,“ continued Mr Baumann. “We noted a continuous theme was that users need a sturdy and reliable pipettor with sufficient battery charge.” One insight gained from the survey has already been used by Integra to further develop their popular PIPETBOY pipettor range. Several respondents indicated that their workflow would be enhanced if you could ‘park’ the pipettor with inserted pipette. As a consequence Integra has introduced a PIPETBOY stand allowing the user to do precisely this.


The PIPETBOY can be used with plastic or glass pipettes with volumes of 1-100ml. Finely regulating pipetting is simply achieved by applying varying finger pressure to the operating buttons and by adjusting the pump speed. The PIPETBOY is powered by a high performance NiMH battery that alerts you when it needs recharging. To avoid contamination from accidentally aspirated liquids the PIPETBOY is protected by a filter. The PIPETBOY comes in several different colours that users can assign to a particular application/user thereby avoiding mix-ups.


Circle no. 441


LABORATORY PRODUCTS


Customer Knowledge Collected to Improve Pipetting Aid


Sheding Light on Innovative Scientific Solutions


The Autumn leg of PerkinElmer, Inc’s 2009 European ‘For the Better’ Tour is now underway. At these informative seminars, scientists, industry leaders and PerkinElmer specialists will share their applications expertise and demonstrate how the latest PerkinElmer solutions can enhance results accuracy in sectors as diverse as environmental analysis, food safety, polymers and chemicals.


With the intent of arming attendees with cutting-edge information and support, the autumn programme kicks off in Lyon, France on October 15. The European seminars will take place in major cities across France, Spain, Italy, Germany and Austria, with additional dates planned later in the year. Further information about the tour and agendas are available at www.perkinelmer.com/forthebettertour.


Each ‘For the Better’ seminar will offer a unique segment-specific agenda, developed by PerkinElmer’s regional specialists and delivered in local language. Guest industry speakers will join experts from PerkinElmer to explore current trends and issues affecting a range of sectors – from pharmaceutical, environmental analysis and food safety to polymers and chemical, energy and children's product safety.


The seminars will also demonstrate how solutions from PerkinElmer can be employed to improve productivity and performance through multiple techniques, including atomic and molecular spectroscopy, chromatography, mass spectrometry and thermal analysis.


Circle no. 440 Contact: sales@intlabmate.com


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LAB ASIA - NOVEMBER/DECEMBER 2009 - LABORATORY PRODUCTS


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