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By Heather Hobbs BRINGING YOU THE LATEST RESEARCH & EVENTS NEWS FROM THE SCIENCE INDUSTRY Vijay Tiwari Receives Bruno Speck Award 2013


Dr Vijay Tiwari, a Group Leader at the Institute of Molecular Biology (IMB) in Mainz, has been awarded the Bruno Speck Award by the Swiss Foundation of Haematological Research. The award recognises outstanding work by young scientists in the fields of haematology and stem cell research.


Dr Tiwari received the award in recognition of his research into stem cell differentiation and the role of direct histone modification by the signalling molecule JNK in this process. This discovery provided the first evidence that chromatin can be directly affected by kinase signalling molecules. This represents a novel mechanism by which genes can be regulated. As JNK is involved with a signalling pathway that is impaired in many types of cancer, this research may pave the way for the development of new cancer therapies.


The research was conducted while Dr Tiwari was studying chromatin modification in the laboratory of Dirk Schübeler at the Friedrich Miescher Institute for Biomedical Research (FMI) in Basel, Switzerland. It was carried out in collaboration with FMI’s Michael Stadler and Renato Paro from the Department of Biosystems Science and Engineering from ETH Zürich.


Dr Tiwari is now continuing this research at IMB. Here his group is investigating the mechanisms by which epigenetic machinery and regulatory factors contribute to the transcriptional reprogramming that defines cell-type, and is identifying how this communication is altered in diseases such as cancer.


Dr Tiwari’s research was published in Nature Genetics Find out more circle no. 5


Mercury 2013 to Examine Effectiveness of Global Treaty


A legally binding agreement to reduce global mercury emissions was signed by 140 countries in January this year, amid delight that an important milestone had been reached in the control of toxic mercury emissions. However, the effectiveness of the treaty will be assessed by a panel of experts during ‘Mercury 2013’ - the International Conference on Mercury as a Global Pollutant (ICMGP) which will take place in Edinburgh, Scotland, from 28th July – 2nd August 2013.


The negotiations which led to the development of the treaty were convened by the UN Environment Programme (UNEP) and the signatories will implement controls and reductions across a range of products, processes and industries where mercury is used, released or emitted. These range from thermometers and energy-saving light bulbs to emissions from the mining, cement and coal-fired power sectors. The treaty also addresses the direct mining of mercury, export and import of the metal and safe storage of waste mercury.


Mercury and its various compounds have a range


create standardised and replicable methods for monitoring the effectiveness of efforts to reduce mercury among different countries of the world; How to best communicate information about progress; What basic components are needed for cost-effective and customised national plans for monitoring; and Where standardised monitoring stations should be located.


of serious health impacts including brain and neurological damage especially among the young.


Susan Egan Keane of the Natural Resources Defense Council in the United States, and Dr. David Evers a leading wildlife toxicologist will co- chair a session at Mercury 2013 entitled ‘Evaluating the effectiveness of the Global Mercury Treaty’.


A panel comprised of scientists and policy makers will explore the gaps, needs, hurdles, government participation and scientific capacity (especially in the developing world) for creating a global mercury monitoring system that can evaluate the effectiveness of the new mercury treaty.


The panel will discuss issues such as: How to


Panel topics will include (a) monitoring changes in the largest source of mercury pollution - artisanal small-scale gold mining; (b) monitoring changes in environmental mercury resulting from treaty actions, using the Global Mercury Observation System; and (c) evaluating changes in human exposure through bio-monitoring.


As the importance of mercury as a pollutant becomes better understood, Mercury 2013 is likely to generate a great deal of interest in the UK. However as a global event, between 800 - 1200 delegates wil travel to Scotland from all over the world.


Registration is now available at: www.mercury2013.com


Find out more circle no. 6


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