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Bringing you the latest Business News updates from the science industry


by Heather Hobbs Queen’s Award for NanoSight


Nanoparticle characterisation technology manufacturer NanoSight has been selected to receive the Queen's Award for Enterprise - Innovation in 2013.


The company was founded in 2004 by Dr Bob Carr and John Knowles, after Carr discovered a technology which allows particles, small enough to be below the resolution limit of normal optical microscopes, to be visualised, sized and counted without the need for an electron microscope.


Mrs Sarah Troughton, Lord-Lieutenant of Wiltshire, presenting NanoSight CTO, Bob Carr, with the Queen's Award for Enterprise: International Trade 2012


Since 2005, NanoSight has grown sales by more than 60% annually, year on year, and now employs 47 people worldwide. The most significant growth has been in pharmaceuticals and life sciences, where budgets have remained largely unaffected by the


global financial condition, the company said. There are now more than 600 NanoSight instruments in use worldwide, with the firm’s products having been cited in academic papers said to total over 700.


Speaking about the importance of this award, Dr Carr said "Winning this award is further recognition of our Nanoparticle Tracking Analysis (NTA) technique as an outstanding technology to meet the needs of the burgeoning nanomaterials sector. It is reward to our team at Salisbury who continue to innovate both hardware and software improvements to meet the challenging demands of our users."


The company also received a 2012 Queen's Award for Enterprise - International Trade.


MORE INFO. 43 Irish Venture to Deliver Biodegradable Implants


A consortium of three Irish biomedical companies - Venn Life Sciences Holdings Plc, Cellulac Ltd and Biopharmed West Ltd have announce a joint venture to pursue the development of biodegradable human implants. The joint venture provides a complement of expertise beginning at traceability and processing of raw materials to finished medical grade PolyLactic Acid, (PLA), a component in the manufacture of implanted medical devices in the operating theatre. Product range is potentially from


internal sutures to orthopaedic bone regeneration implants providing a clean technological solution for the replacing of titanium.


Venn Life Sciences is to provide clinical trial management and resourcing solutions to pharmaceutical, biotechnology and medical device clients. Cellulac Ltd, currently involved in a major EU project involving potential uses of biobased chemicals from lignocellulose and alga, will provide


the scientific laboratories, production and clean room infrastructure, quality controls and access to its portfolio of patents in the production of biodegradable PLA. Partners in this project include Fraunhofer Institiute, Nova Institute and Wageningen University.


Biopharmed West Ltd will contribute institutional, commercial know-how and management of distribution channels


MORE INFO. 44 Novasep Redefines Safety Properties of Reagent


Research scientists at Novasep, a leading supplier of synthetic molecules and biomolecules, recently discovered and characterised the explosive properties of the Togni reagent II and intermediates at the company’s Leverkusen site in Germany. Togni reagent II (1-(trifluoromethyl)-1,2- benziodoxol-3(1H)-one, 1) is a versatile reagent for the electrophilic introduction of trifluoromethyl groups. It is used in pharmaceutical manufacturing and also widely used in universities.


Authorised by the German Government to handle energetic materials and operate hazardous reactions


from lab to thousands tons scale, Novasep conducted a Koenen test on a sample of Togni Reagent II prepared in their kilolab, in which the reagent was shown to be highly explosive. Another critical property of the Togni Reagent II clarified by the Novasep team is its fast combustion when ignited. The combustion factor was measured as BZ6, the same classification as black powder.


This discovery has resulted in a revised classification for handling and transportation of the Togni reagent II, which must now be approved by national competent authorities. Novasep has also informed companies


known to market the compound, who will relay the safety measures required to handle the reagent.


“The work completed by Novasep regarding the Togni Reagent II will contribute to a more deliberate and responsible handling of the reagent used by so many research groups," said Professor Togni, professor of organometallic chemistry at the Laboratory of Inorganic Chemistry, ETH Zurich and inventor of the reagent.


The findings were published in the March edition of the journal Organic Process Research and Development.


MORE INFO. 45


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