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Faster Characterisation of Enzymes with Micro-Volume Analysis Instrument The DSM Biotechnology Centre, based in Delft, Netherlands, is taking advantage of Avacta Analytical’s Optim®
1000 micro-volume protein analysis
instrument to characterise enzymes for use in the food industry. Mark Stor, an associate scientist in the applied biochemistry department, explained: “Enzymes are sold on an activity basis, and that requires biochemical characterisation to establish what the enzyme looks like and how it behaves. We need to know the limitations of each enzyme to determine which applications it is most suitable for.”
“We saw the Optim at some laboratory fairs, and were interested in its ability to run temperature gradients and produce stability profiles. This is really important for us; stability is always an issue with enzymes. If an enzyme is produced at 30°C, will it also work at 60°C? We have to test the enzyme to establish its limits, looking at its activity at different temperatures and in a range of formulations. To do this manually is extremely time consuming, but using the Optim it is possible to study 96 formulations in a day, obtaining a complete temperature profile that gives an indication of the most stable products. It is much quicker, and reduces the amount of work required. We can screen samples more quickly and, in the future, may even be able to replace lengthy shelf life studies.”
MORE INFO. 150
New Safety Enclosure Provides Controlled Laboratory Environment
Available from Asynt Ltd, the Lab-Bubble™ is a versatile piece of containment equipment that can be used to provide many different types of safety or controlled environments simply by using additional components to change the function of the enclosure. The Lab-Bubble™ is designed and tested in various configurations for applications including handling of chemicals and powders, weighing, biological sample handling and PCR preparation. The environment in the Lab-Bubble™ can be controlled for humidity (20-55% RH) using a dry Nitrogen glove box and temperature (15- 30°C). The air extraction on Lab-Bubble™ is provided via a small box section fan filtration system that incorporates a safe change HEPA / carbon combination filter. Affordably priced - Lab-Bubble™ can be used as a simple storage unit and also as a demonstration/ teaching unit. The construction of the main body of Lab-Bubble™ is from 6mm clear moulded cast acrylic that ensures excellent visibility and is easily cleaned. The base section is durably constructed from chemically resistant, 10mm thick High Density Polyethylene. (HDP).
MORE INFO. 151 MORE INFO. 152
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