jaaha.org / JAAHA VMI Veterinary Management Institute RETROSPECTIVE STUDIES
A Review of 18 Cases of Feline Colonic Adenocarcinoma Treated with Subtotal Colectomies and Adjuvant Carboplatin
TA Arteaga, J McKnight, PJ Bergman
ABSTRACT Feline colonic adenocarcinoma is a locally invasive, highly metastatic tumor that is most often treated with wide surgical excision (subtotal colectomy) and systemic chemotherapy either with or without nonsteroidal anti- inflammatory medications. In this retrospective study, the outcome of subtotal colectomy and adjuvant carbo- platin in 18 client-owned cats is described. The median carboplatin dose was 200 mg/m2 (range, 200–254 mg/ m2) q 4 wk with a median of five doses/cat (range was two to seven doses/cat). Limited toxicities were noted. Positive prognostic factors for the disease-free interval included cats that had weight loss as a presenting sign (P , 0.036) and negative prognostic factors for median survival included nodal and 2 distant metastasis (178 versus 328 days and 200 versus 340 days, respectively). The median disease-free interval was 251 days (range, 37–528 days) and the median survival time was 269 days (range, 40–533 days). Subtotal colectomy and adjuvant carboplatin is a safe and potentially effective treatment for cats with colonic adenocarcinoma.
RETROSPECTIVE STUDIES
Ultrasonographic Evaluation of Canine Supraspinatus Calcifying Tendinosis
MLA Mistieri, A Wigger, JC Canola, JGP Filho, M Kramer
ABSTRACT Supraspinatus calcifying tendinosis is an uncommon finding in dogs. Although its radiographic appearance has been described previously, radiographs alone do not provide detailed information about the tendon parenchyma. Tendon ultrasonography has been widely applied for the diagnosis of human tendinosis, but it remains underused in dogs. This article reviews the ultrasonographic technique and variable appearance of canine supraspinatus calcifying tendinosis observed in 33 tendons. The ultrasonographic findings are de- scribed. The most common ultrasonographic finding was a hyperechoic area accompanied by distal acoustic shadowing. No relationship with bicipital tenosynovitis was found. A color Doppler examination was possible in only five of the tendons, revealing no blood flow in those tendons. There was evidence that the presence of a hypoechoic area surrounding the calcification was related to clinical signs of pain, suggesting an active in- flammatory process. Ultrasonography was an excellent technique to evaluate lesions of the supraspinatus ten- don and it revealed details not apparent on radiographs.
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