50 | Sector Focus: Preservatives & Fire Retardants


SUMMARY


■Arxada uses metagenomic DNA Analysis to assess how well proposed active ingredients work


■Tanasote S40 is the first wood preservative to make use of a new class of actives


■In the development of Tanasote S40, Arxada conducted additional laboratory fungal decay tests


■Arxada is working on products to launch through 2030 and beyond


LESSONS IN CHEMISTRY


Dr Stephen Uphill looks at the chemistry that drives wood preservation


The world of wood preservation is based on innovative chemistry. Companies rarely get the opportunity to share the laboratory work that forms the majority of any Biocidal Products Regulation (BPR) efficacy package because the focus in industry press tends to be on the treated wood. In this article, Dr Stephen Uphill, Arxada’s technical lead for wood protection, provides a taste of what is scientifically involved in the development of a biocidal product for use as a wood preservative (PT 8).


ASSESSMENT OF ACTIVE INGREDIENTS A biocidal product comprises of active ingredients which provide an effect on one or more target organisms relevant to the use being considered. At Arxada we use metagenomic DNA Analysis to assess how well proposed active ingredients work to inhibit the growth of target organisms that cause wood decay. Our goal is to provide the most efficacious wood preservatives on the market, that are more sustainable and have minimal impact on the environment, human and animal health.


Above: Oxford nanopore GridION metagenomics equipment TTJ | November/December 2024 | www.ttjonline.com


For the metagenomic DNA Analysis, the Arxada research and development team use an Oxford Nanopore GridION sequencer to read DNA sequences one base at a time, as the DNA passes through a tiny hole, the ‘nanopore’. The resulting sequences are compared against the Arxada custom DNA database, which allows us to identify fungi, bacteria, archaea, viruses, and other organisms that are present in our samples. The application of this technique allowed


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