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25 MARCH 2018 HEALTHCARE INNOVATIONS


SPECIALIST CLINICS 27


The Oncofocus test detects DNA mutations unique to a person’s cancer and matches them with the appropriate targeted therapy thereby allowing your doctor to prescribe the most effective treatment and minimise unnecessary side effects. The Oncofocus test can be used for all types of cancer except for lymphomas and leukemia.


CANCER: WHICH THERAPY?


• Applicable to all solid tumours • Performed on routine histology samples


Oncofocus® REPORT INCLUDES • FDA and EMA approved therapies • ESMO and NCCN guidelines • Therapies in clinical trials worldwide


Suite 15-16, The Science Village, Chesterford Research Park Cambridge, CB10 1XL


+44 (0) 1223 785 327 - info@oncologica.com www.oncologica.com


The Oncofocus test detects DNA mutations unique to a person’s cancer and matches them with the appropriate targeted therapy thereby allowing your doctor to prescribe the most effective treatment and minimise unnecessary side effects. The Oncofocus test can be used for all types of cancer except for lymphomas and leukemia.


WHAT ARE TARGETED THERAPIES? WHAT ARE TARGETED THERAPIES?


Targeted therapies are new drugs that kill cancer cells but do not affect normal cells compared with chemotherapy which kills both cancer cells and normal cells.


NEW PRECISION ONCOLOGY TEST TO IDENTIFY THE MOST EFFECTIVE ANTI-CANCER TREATMENT


Targeted cancer therapies are the cornerstone of personalised medicine, a form of medicine that uses information about a person’s DNA profile to treat cancer.


WHAT ARE TARGETED THERAPIES? WHAT ARE TARGETED THERAPIES? 1


1


Targeted therapies are new drugs that kill cancer cells but do not affect normal cells compared with chemotherapy which kills both cancer cells and normal cells. DETECTION OF MUTATIONS


Targeted therapies are new drugs that kill cancer cells but do not affect normal cells compared with chemotherapy which kills both cancer cells and normal cells.


1


EVERY PERSON’S CANCER IS UNIQUE EVERY PERSON’S CANCER IS UNIQUE


1


EVERY PERSON’S CANCER IS UNIQUE EVERY1 PERSON’S CANCER IS UNIQUE


1


Every person’s tumour is unique due to the different types of cancer DNA mutations acquired during the development of the disease.


2 3 IDENTIFICATION OF APPROPRIATE TARGETED THERAPIES


A wide range of targeted drugs have been developed (>600) against each of these different types of DNA mutations.


BASED ON CLINICAL EVIDENCE The Oncofocus test is fully validated for clinical use and the information it provides is entirely based on clinical evidence.


3 IDENTIFICATION OF APPROPRIATE TARGETED THERAPIES


TARGETED THERAPY VS CHEMOTHERAPY TARGETED THERAPY VS CHEMOTHERAPY


EASY TO PERFORM


TARGETED THERAPY VS CHEMOTHERAPY EASY TO PERFORM


EASY TO PERFORM TARGETED THERAPY VS CHEMOTHERAPY 3 IDENTIFICATION OF APPROPRIATE TARGETED THERAPIES


Oncofocus is performed on the routine biopsy used to make your initial diagnosis and held at your hospital, so there is no requirement for another biopsy or hospital visit for this test. All that is required is that you or your doctor completes a test request form for the “Oncofocus test”. Oncologica will take care of the collection of your sample.


BASED ON CLINICAL EVIDENCE The Oncofocus test is fully validated for clinical use and the information it provides is entirely based on clinical evidence.


QUICK RESULTS Oncofocus results will be ready within 10 working days following receipt of the sample at Oncologica and the report will be sent directly to you and your oncologist or general practitioner.


Every person’s tumour is unique due to the different types of cancer DNA mutations acquired during the development of the disease.


Every person’s tumour is unique due to the different types of cancer DNA mutations acquired during the development of the disease.


A wide range of targeted drugs have been developed (>600) against each of these different types of DNA mutations.


2 2 3 3


A wide range of targeted drugs have been developed (>600) against each of these different types of DNA mutations.


A wide range of targeted drugs have been developed (>600) against each of these different types of DNA mutations.


BASED ON CLINICAL EVIDENCE The Oncofocus test is fully validated for clinical use and the information it provides is entirely based on clinical evidence.


Oncofocus is performed on the routine biopsy used to make your initial diagnosis and held at your hospital, so there is no requirement for another biopsy or hospital visit for this test. All that is required is that you or your doctor completes a test request form for the “Oncofocus test”. Oncologica will take care of the collection of your sample.


QUICK RESULTS Oncofocus results will be ready within 10 working days following receipt of the sample at Oncologica and the report will be sent directly to you and your oncologist or general practitioner.


The


Oncofocus is performed on the routine biopsy used to make your initial diagnosis and held at your hospital, so there is no requirement for another biopsy or hospital visit for this test. All that is required is that you or your doctor completes a test request form for the “Oncofocus test”. Oncologica will take care of the collection of your sample.


QUICK RESULTS Oncofocus results will be ready within 10 working days following receipt of the sample at Oncologica and the report will be sent directly to you and your oncologist or general practitioner.


Targeted therapies are much more effective than chemotherapy because they have been designed to specifically hit their target mutations which are present only in cancer cells. This means normal cells are unaffected by the treatment thereby minimising toxic side effects.


of these drugs are pills that are given orally and therefore don’t require hospital admission.


Targeted therapies are much more effective than chemotherapy because they have been designed to specifically hit their target mutations which are present only in cancer cells. This means normal cells are unaffected by the treatment thereby minimising toxic side effects.


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Chemotherapy on the other hand affects both normal cells and cancer cells. The killing of normal cells results in serious side effects such as hair loss, nausea and vomiting, infections and anaemia. The majority of chemotherapeutic drugs are given by infusion and therefore require hospital admission.


Targeted therapies are much more effective than chemotherapy because they have been designed to specifically hit their target mutations which are present only in cancer cells. This means normal cells are unaffected by the treatment thereby minimising toxic side effects.


of these drugs are pills that are given orally and therefore don’t require hospital admission.


In addition, most


of these drugs are pills that are given orally and therefore don’t require hospital admission.


Chemotherapy on the other hand affects both normal cells and cancer cells. The killing of normal cells results in serious side effects such as hair loss, nausea and vomiting, infections and anaemia. The majority of chemotherapeutic drugs are given by infusion and therefore require hospital admission.


Chemotherapy on the other hand affects both normal cells and cancer cells. The killing of normal cells results in serious side effects such as hair loss, nausea and vomiting, infections and anaemia. The majority of chemotherapeutic drugs are given by infusion and therefore require hospital admission.


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Chemotherapy on the other hand affects both normal cells and cancer cells. The killing of normal cells results in serious side effects such as hair loss, nausea and vomiting, infections and anaemia. The majority of chemotherapeutic drugs are given by infusion and therefore require hospital admission.


In addition, most In addition, most


Targeted therapies are much more effective than chemotherapy because they have been designed to specifically hit their target mutations which are present only in cancer cells. This means normal cells are unaffected by the treatment thereby minimising toxic side effects.


In addition, most


of these drugs are pills that are given orally and therefore don’t require hospital admission.


Targeted cancer therapies are the cornerstone of personalised medicine, a form of medicine that uses information about a person’s DNA profile to treat cancer.


DNA/RNA EXTRACTED FROM TUMOUR SAMPLE


Targeted cancer therapies are the cornerstone of personalised medicine, a form of medicine that uses information about a person’s DNA profile to treat cancer.


Every person’s tumour is unique due to the different types of cancer DNA mutations acquired during the development of the disease.


3


DNA/RNA EXTRACTED FROM TUMOUR SAMPLE


2 2 DETECTION OF MUTATIONS


Targeted cancer therapies are the cornerstone of personalised medicine, a form of medicine that uses information about a person’s DNA profile to treat cancer.


DNA/RNA EXTRACTED FROM TUMOUR SAMPLE


2


The Oncofocus test detects DNA mutations unique to a person’s cancer and matches them with the appropriate targeted therapy thereby allowing your doctor to prescribe the most effective treatment and minimise unnecessary side effects. The Oncofocus test can be used for all types of cancer except for lymphomas and leukemia.


Targeted therapies are new drugs that kill cancer cells but do not affect normal cells compared with chemotherapy which kills both cancer cells and normal cells. DETECTION OF MUTATIONS


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