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Laboratory Products 33 Supercritical CO2 – A Green Solvent for the Pharmaceutical & Food Industries


The need for new and clean technologies for processing ultra-pure pharmaceutical and food products has led to a rapid rise in the use of supercritical CO2


. This allows you to refi ne compounds without either leaving toxic residues behind or risking thermal degradation of the products. Traditional solvents carry with them high costs plus signifi cant health, environment and safety hazards.


The vapour permeability of both the processes’ materials and the materials being refi ned, become increasingly important and Versaperm has developed an instrument to measure this both quickly and accurately. The favourable transport properties of supercritical CO2


vv allows deeper penetration into a


compound’s matrix and more effi cient and faster extraction than with conventional organic solvents. Additionally, modern powder generation processes often involve crystallisation with supercritical fl uids.


Versaperm’s equipment is fast, accurate in the parts per million to billion ranges and simple to use. Because supercritical CO2 can fl ow through many solid barriers in a way that can be very sensitive to small temperature and pressure variations, it can also allow users to control these factors very precisely.


The equipment can measure several samples at the same time and provides a simple to use automated control panel with a large touch-screen interface. It needs very little re-calibration and requires, at most, minimal training. Supercritical CO2


can be used for everything from the processing of coffee and vegetable oil through to Insulin and anti-asthma drugs. It can even be used to produce Biocrude, a next-generation non-fossil fuel. As well as designing, manufacturing and supplying the equipment to laboratories, including standards laboratories around the world, Versaperm also offers laboratory testing service and consultancy services. More information online: ilmt.co/PL/6PZX


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Liquid Handling Solutions for Every Application


Poulten & Graf offer an excellent range of reliable products for all your liquid handling requirements. Whether you are looking for a manual or automatic process or if it is for handling aqueous solutions or aggressive acid the company have the right device for your application.


Over the years Poulten & Graf have gained extensive experience in the production of manual bottle top dispensers and automatic dosing systems. The products are not only indispensable in everyday life in the laboratory, but they are also easy to use, safe and precise.


Poulten & Graf are proud to present their wide product range, which extends from bottle top dispensers to an automatic dosing system. These cover most laboratory applications and are also suitable for chemical and pharmaceutical manufacturing uses as well. Poulten & Graf have the widest product range of liquid handling products on the laboratory market and offer real choice and expertise to customers. The company’s product range includes the brands of FORTUNA®


OPTIFIX® and POLYFIX®


Dispensers and staff are experts at providing the most suitable solution. To assist in


choosing the right Poulten & Graf liquid handling device for your application, a chemical resistance list has been published and can be downloaded from the company website. More information online: ilmt.co/PL/Po4e


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Convenient Buffer Removal Ensures Safer COVID-19 ELISA Testing The COVID-19 pandemic has led to the


development of a number of novel RT-PCR based tests to detect the SARS-CoV-2 virus in patients. As the situation has progressed, there is now a need for serology tests to evaluate the immune response of patients, as well as to assess immunity in the general population. These immunoassays are critical to allow movement restrictions to be eased and prevent a second peak in infections.


Most serological tests are based on sandwich ELISA techniques to detect antibodies against the virus in patients that have recovered from COVID-19. The protocols for these ELISAs require several aspiration steps to remove


buffers after incubation and washing, and the safest way to perform this is using an instrument such as Integra Biosciences’ VACUSIP portable aspiration system.


There are many advantages to using an aspiration system to remove buffers from samples, especially for 96 well plate formats, where there are multiple wells to process. These instruments enable safer, faster and more convenient waste removal than with a multichannel pipette, and the aspirated waste goes directly into the collection bottle, avoiding the risk of spillages or exposure to biohazardous waste, an important factor when handling infectious samples.


The compact design of the VACUSIP system means it can fi t on any bench or into any safety cabinet, offering the fl exibility to be used wherever needed. With a hydrophobic fi lter to protect against contamination, and a fully autoclavable liquid path for easy decontamination, the VACUSIP is the ideal aspiration system for laboratories working with SARS-CoV-2 samples.


More information online: ilmt.co/PL/EpxR 52499pr@reply-direct.com


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