Mass Spectrometry
New Portable Quadrupole Analyser Introduced
Hiden Analytical introduces the new pQA portable gas analyser, a versatile mass spectrometer offered with a range of interchangeable sampling inlets to suit a broad application range. MIMS inlets are offered for analysis of dissolved species in ground water, fermentation cultures, soil samples, and general applications where analysis of dissolved species in liquid sample is required. The system is suited to gas analysis applications, where sample volume is small, and for environmental applications where detection of low concentration levels is required. The pQA system has a mass range of 200 amu and sub ppb detection levels. Extended mass range to 300amu is optional.
The system is supplied in a Pelican® case and can be powered by a 12 V supply for field use, battery and/or solar powered, or a 220 V supply for laboratory use.
More information online:
ilmt.co/PL/3kRG 52445pr@reply-direct.com
New Triple Quadrupole MS Combines World-class Sensitivity and Ultra-high Detection Speed
Shimadzu has released the LCMS-8060NX triple quadrupole mass spectrometer. Together with world-class sensitivity and detection speeds, this flagship LC-MS system offers further improvements in ease-of-use and robustness. It offers greater operating efficiency to pharmaceutical companies needing to shorten drug discovery periods or reduce costs, clinical firms that handle complex biological samples, and entities in food science involved in investigating residual pesticides among others. The LCMS-8060NX enhances method development and routine analysis.
The LCMS-8060NX offers among the highest sensitivity and detection speeds in the world and includes internal mechanical improvements to promote sample ionisation. This enables high-sensitivity analysis even for compounds that are difficult to ionise.
The newly introduced IonFocus unit reduces instrument contamination by guiding ions to the interior more efficiently and removing unwanted components, which helps to prevent decreases in detection accuracy or sensitivity. In addition, more robust components are used in ion-focusing, enabling more reliable analysis. The LCMS-8060NX therefore offers both higher sensitivity analysis and lower downtime.
The system includes several ‘Analytical Intelligence’ functions to maximise analysis throughput and improve the operational efficiency and
productivity of the entire workflow, from preparations for analysis through to data processing. For example, the LCMS-8060NX includes a new ionisation unit that is capable of high-sensitivity analysis without the need for complicated adjustments and enables more efficient method development, as well as functions to start up or shut down analytical instruments automatically in combination with a Shimadzu Nexera LC system.
Shimadzu’s powerful LC-MS range from single to triple quadrupole systems enables more compounds to be screened in less runs while increasing sensitivity and data quality. Many accessories, software, data banks and method packages complement the systems. Depending on the need for sensitivity in the lab, one model always fits, bringing robustness while keeping the flexibility to upgrade at a later stage as soon as requirements change.
More information online:
ilmt.co/PL/1ZXG 52450pr@reply-direct.com
Extended Capability and Power for High-Resolution Mass Spectrometers Announced
Waters Corporation has announced a new fragmentation technique and an imaging option for its high-resolution mass spectrometers giving research scientists working across a broad range of end markets including biomedical, biopharmaceutical and food research, greater experimental freedom to explore the intricacies of peptides, proteins, and protein complexes.
“This is a time for science to step up and show what it can do for humanity,” said James Langridge, PhD, Senior Director, Advanced Mass Spectrometry, Waters Corporation. “Understanding the biology of disease and discovering new treatments requires us to continue innovating new and powerful capabilities for mass spectrometry so that scientists can accurately and confidently answer their scientific questions.”
For its high-performance SELECT SERIES™ Cyclic™ IMS System, Waters will offer scientists the ability to probe the structure of proteins, peptides, glycans and other biomolecules with Electron Capture Dissociation (ECD), a fragmentation technique made available through a partnership with e-MSion, Inc.
ECD combined with ion mobility mass spectrometry and Collision Induced Dissociation (CID) available with the Cyclic IMS System, gives scientists improved sequence coverage for native proteins and surrogate peptides and additional structural information about larger proteins that might not have been possible before.
For the first time, the new Desorption Electrospray Ionization DESI XS source is available on the Waters SELECT SERIES Cyclic IMS, SYNAPT™ XS, and Xevo™ G2-XS QTof Mass Spectrometers. Waters acquired the rights to DESI™ IP from Prosolia, Inc. and the Purdue Research Foundation in 2018, making Waters the exclusive provider of this technology. The new Waters DESI XS source retains the performance of the original version and features enhanced reliability and user experience, making high quality MS imaging accessible to a broader range of scientists.
The ECD and DESI XS options for the SELECT SERIES Cyclic IMS System will ship in the fourth quarter of this year. Existing Waters Cyclic IMS customers will also be able to add these new options to their instruments at the same time. DESI XS is now available to ship with new Xevo G2-XS QTof and SYNAPT XS Systems. It is also available as an upgrade option for previously installed Xevo G2-XS QTof and SYNAPT XS systems.
More information online:
ilmt.co/PL/Q0nn 52592pr@reply-direct.com
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