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interfere with the separation and/or cause carryover problems is used.
As the need for fast screening methods that rely upon chromatographic separations continues to increase, the speed of every aspect of the analytical technique must be examined. Novel strategies that employ higher throughput sample introduction will be a critical aspect of the next generation of rapid measurement tools. Whether the next generation of sample injection is based upon parallel sampling, segmented flow, or some other technique is yet to be identified, most practitioners of ultrafast chromatography agree that it is a major bottleneck to be overcome. For now, the advances that have brought autosampler cycle times below 10 seconds still represent an outstanding improvement from previous instrument generations and can still facilitate higher throughput analysis in nearly any lab that relies upon LC.
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