Mass Spectrometry & Spectroscopy 19 Powerful Package for Sample Prep to XRF Analysis


Retsch, a leading solution provider for sample homogenisation and characterisation, has added a new pellet press to its product range. The PP 35 is a compact benchtop model which uses a maximum pressure force of 35 tons to produce smooth and stable pellets suitable for XRF analysis.


Before the sample can be pressed to a pellet, it needs to be ground to a homogeneous fineness below 100 microns. The MM 400 mixer mill is ideally suited for homogenising up to 8 x 30 ml sample material quickly and


reproducibly. If the sample needs to be mixed with a binding agent for stability, this can be done in conical centrifuge tubes which are clamped into a special adapter.


For the homogenisation of larger volumes of hard and brittle sample materials, Retsch offers two models of Vibratory Disc Mills, RS 200 and RS 300 XL. These achieve grind sizes below 100 microns within seconds and are therefore highly suitable for pulverising samples for pelletising. Pellet presses with 25 t and 40 t maximum pressure force complete Retsch’s offering for quick and reproducible preparation of XRF samples.


To ensure accurate and reproducible XRF analysis results, the sample needs to have a uniform particle size distribution and the pellet needs to be as dense as possible. Both requirements are easily met when using Retsch’s powerful package for sample preparation to XRF analysis.


43633pr@reply-direct.com New XRD System Announced


The D8 DISCOVER Plus from Bruker combines the high power of the new TXS-HETM SourceTM


and accuracy of the new high endurance ATLASTM


goniometer.


The TXS-HE is optimised to deliver an extremely high intensity X-ray beam without compromising flexibility to meet the most demanding analytical needs in today’s research, development and process control. The TXS-HE significantly reduces data collection time compared to


conventional X-ray sources and delivers better data quality, giving new insights into structural properties of investigated materials. Further, the additional speed of the TXS-HE enables the studies of dynamic processes including time dependent phase transitions and kinetics in materials better than ever before.


The advanced design of the new ATLAS goniometer delivers an even higher level of angular positioning accuracy, thus increasing the reliability of measured data for all applications. It is extremely robust ensuring that this level of performance is maintained for all configurations from classic powder diffraction to epitaxial thin-film characterisation. As a result, the D8 DISCOVER Plus with ATLAS goniometer even tops Bruker’s unique total system alignment guarantee, setting the new standard for XRD laboratory systems.


By combining the high X-ray flux of the TXS-HE, the outstanding accuracy of the ATLAS goniometer, and the large detection area and dynamic range of the new EIGER2 R 500K multi-mode Hybrid Photon Counting (HPC) detector, the D8 DISCOVER Plus offers unmatched capabilities for the analytical tasks in materials research and analysis.


“With the introduction of the D8 DISCOVER Plus, Bruker once again sets new standards in XRD instrumentation. The D8 DISCOVER Plus is designed to deliver top-class results for structure analysis of all kinds of materials, from powders in the pharmaceutical industry to crystalline structures in semiconductor devices, and is a further step to strengthen Bruker’s position as the provider of the most powerful and user-friendly XRD solutions on the market,” stated Dr Lutz Bruegemann, General Manager XRD and Vice President of Bruker AXS.


43896pr@reply-direct.com Characterisation and Quality Control of MBE Processes


Hiden Analytical present a family of quadrupole mass spectrometer-based diagnostic instruments with specific application to the molecular beam epitaxy process and to post-process thin film evaluation, with primary features highlighted in their new MBE process-specific technical information sheet.


In-process probes are specifically constructed for operation in the reactive molecular beam deposition environment, using low-reactivity construction materials and with extensive surface screening. Instruments includes the HALO MBE residual gas analyser, the XBS molecular beam deposition rate monitor with ion beam acceptance through a 70ºC cone angle, and a modular SIMS surface analysis tool with integrated fine-focus ion gun for in-process surface layer evaluation.


The AutoSIMS system is offered for measurement of post-process surface layer composition and for depth profile compositional changes through depths typically up to a micron. The system has an interchangeable cassette-style multi-sample holder with automated X-Y positioning stage enabling fully automated unattended operation. The fine-focus ion gun is both oxygen and argon compatible.


For full details on this or any other Hiden Products visit www.hidenanalytical.com. 44896pr@reply-direct.com


high-efficiency Turbo X-ray with the unrivalled reliability


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Evaporative Sample Preparation for Mass Spectrometry


Genevac has established a new web page that brings together customer technical articles that illustrate how centrifugal evaporation has become a sample preparation technique of choice for laboratories that seek to analyse complex samples using hyphenated mass spectrometry techniques.


Many laboratories still rely upon the use of a rotary evaporator to perform the evaporation part of their sample preparation protocol prior to LC-MS or GC-MS analysis. While rotary evaporator methods often give good recoveries, they can only handle a single sample, require continuous monitoring to control the process and to ensure that no foaming or bumping occurs.


For labs involved with GC-MS or LC-MS – Genevac SampleGenie™ technology in conjunction with a Rocket Synergy, HT or EZ-2 series evaporator is enabling large sample volumes to be dried directly into vials eliminating several time-consuming sample handling steps and the attendant risk of errors. SampleGenie is proven to reduce evaporation times by up to 66%, is compatible with a wide range of HPLC, GC and storage vial sizes and is a proven methodology for environmental analysis, metabolism and toxicology studies, food and beverage research, drugs of abuse testing as well as post purification protocols in life science research.


Environmental analysis of persistent organic pollutants (POPs), glyphosphates and agal toxins are today a critical requirement in monitoring the quality of municipal water supplies. A paper is available for download that describes how a direct evaporative method developed to replace a solid phase extraction sample preparation technique that has traditionally been used prior to LC-MS-MS analysis of algal toxins in lake water. The authors demonstrate how the direct evaporation sample preparation technique offers distinct advantages over solid phase extraction by eliminating the sample clean-up step, improving reproducibility, decreasing analysis time, minimising waste generation and being more cost effective.


MALDI-TOF Mass Spectrometry is a widely accepted technique for the elucidation and quantitation of biomolecules in life science research. However concentrating oligonucleotides, proteins, antibodies and other large biomolecules prior to analysis is not straightforward. A paper is available for download that describes how Genevac centrifugal evaporators have been able to protect these sensitive samples from thermal degradation and by preventing cross contamination between different samples in a microplate.


To review and download the ‘Evaporative Sample Preparation for Mass Spectrometry’ papers please visit www.evaporatorinfo.com/info24.html.


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