28 New Improved UV Sterilisation Cabinet


The new GLE-UVSC UV Sterilisation cabinet from Scie-Plas is an essential item for every molecular biology laboratory carrying out PCR®


reactions. The cabinet provides decontamination of reagents and equipment before carrying out sensitive PCR® reactions, particularly when amplifying DNA


sequences which are either in limited supply or of low copy number. Four timer-controlled 15- Watt UV bulbs enable the user to control the exposure time and dose of high energy UV irradiation required to denature nucleic acids that cause unwanted background contamination.


A timer override switch allows the UV source to remain on indefinitely if preferred. Safety interlocks switch-off the bulbs automatically when the cabinet doors are opened, preventing accidental exposure to the UV source.


The cabinet's construction from UV-impermeable 10mm acrylic also serves as an effective barrier against radioactive isotopes, allowing the user to work in complete safety with high energy beta- emitters such as 32P. A single white light bulb illuminates the work area when the cabinet is in use. It now comes with universal power input as standard. Interior dimension of the cabinet are: 21.2" (54cm) wide x 15.7" (40cm) deep x 29.5" (75cm)


Circle no. 400


LABORATORY PRODUCTS


New Integrated Equipment for Bulk Production of Freeze-Dried Apis


ADVERTORIAL New Closed-loop Containment Isolator


The new closed-loop containment isolator is the most recent HEPA filtered glove box offered by Plas-Labs. The 830-ABB/CLC contains two (2) 20.32 cm round HEPA filters, magnehelic gauges, blower, and pre-filters.


The glove box operates under a slight negative pressure. The optically clear glove box construction provides optimum light and visibility inside the glove box.


All glove boxes include bright white ambidextrous Hypalon gloves, electrical outlet strip, four (4) valves for purging, and an optically clear cylindrical transfer chamber. Clearly your best choice!


Contact PLAS  LABS at 517-372-7177 for further information.


PLAS  LABS: Clearly Your Best Choice! Circle no. 401


The Telstar Group has developed an integrated automatic system for the bulk production of freeze-dried APIs under isolated conditions. Through this technology, developed for use in the USA by one of the major global pharmaceutical companies, Telstar is now able to implement solutions that combine in-house freeze-drying and containment technologies with those of automatic handling of trays of product.


The system features automatic dispensing of the liquid product, the subsequent unloading of the solid form and automatic transfer to a storage hopper.


Telstar is also developing solutions for the downstream processing following freeze- drying and product unloading, wherein the dry product is dosed into aluminium canisters, with all operations being performed under aseptic conditions inside isolators.


For the bulk production of freeze-dried APIs, Telstar has developed a complete freeze-drying system with automatic handling of product trays under aseptic conditions, integrated into a containment isolator.


Specifically designed for the freeze-drying of materials such as polypeptides, the handling of which can involve a exposure risk for operators, the system incorporates a containment isolator between the product and the operator which allows a level of operator exposure of less than 1µg/m3 to be achieved and maintained throughout the course of an eight-hour shift.


The isolator's main chamber, of vertical laminar flow, contains the mechanisms that automatically feed and extract the product trays from the freeze-dryer chamber. The system features two independent TSCs (Tray Storage Carts); one connected to each side of the main chamber of the isolator, where the product trays are stored once the freeze-dried product has been unloaded.


Following the freeze-drying process, the dry product is removed from the trays using a vacuum system, which transports it to a cyclone where it is separated from the airstream and collected in a hopper, to be transported to the next step in the production process.


In the second phase of the project, Telstar will incorporate into this piece of equipment the sterile downstream process of transferring the solid, freeze-dried product to process stations where it is dosed it into aluminium canisters; all under aseptic conditions within isolators.


Circle no. 402 Circle no. 403


LAB ASIA - MARCH/APRIL 2010 - LABORATORY PRODUCTS


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