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The World’s Tallest Radial Flow Chromatography Column


Finding the Ideal Spectrophotometer


PITTCON NEWS


Selecting a spectrophotometer has never been easier as Biochrom launches its new user-friendly guided navigation as part of the company website, to help customers choose the ideal Biochrom spectrophotometer for their application.


The updated website includes details of the company’s comprehensive portfolio of high performance instruments,


including Biochrom Libra UV-Vis spectrophotometers for industrial, analytical and pharmaceutical laboratories. Biochrom WPA colorimeters and spectrophotometers for education and the life sciences are also included in the knowledge-based selection tool. Visitors to the site will find extensive online information and a comprehensive technical glossary, all designed to inform instrument selection.


Circle no. 342


ADVERTORIAL Complete XRF System


XRF Solutions No Liquid Nitrogen


Proxcys BV announced the installation of the world’s tallest High Performance-Radial Flow Chromatography (HP-RFC) column at Novozymes Biopharma UK. The 165L Stainless steel CRIO- Annular column was supplied together with an automated packing station.


Mr Ashley Wigley, Technical Support Group Manager at Novozymes Biopharma, commented: “Increased Fermenter Yields from our Recombumin®


process have put pressure on our


downstream processing capacity requiring the up-scaling of our initial product capture step. We had over 15 years good working experience with Radial Flow Chromatography Columns and were impressed with the advanced design of the new generation of Proxcys CRIO-Annular columns which further simplify operation, packing and maintenance.


Floor space limitations in our downstream purification suite meant we could expand upwards but not outwards and the solution was a tall thin column. There may be larger Radial Flow Columns in terms of volume or girth but I understand that ours is the tallest Radial Flow Column yet manufactured. Radial Flow Columns give Novozymes Biopharma significant advantages, over the more widely used Axial Flow Columns, with reduced capital cost, shorter delivery time, mechanical simplicity and smaller footprint.”


Mr Marcel Raedts, CEO and President at Proxcys B.V. commented: “Since its launch in 2006, the easy packing and small footprint indeed are prominent features of Proxcys HP-RFC columns. Current frit size limitations resulted in the engineering of a 165-litre bed volume stainless steel CRIO-Annular column featuring an internal column height of 130cm at 12cm bed height, with an empty net weight of only 360kg.


In autumn 2009 the 165L column was packed following the standard protocol within half an hour using the AS-Pack 225 automated packing station. The annular packing resulted in a good packing result at first attempt. Hence with a throughput of 5,000 L/hr at 360cm/hr and a footprint of only 0.75m2


USB Controlled Low Cost Easy to Use


The Amptek XR-100CR with Si-PIN detector or Super XR- 100SDD with Super Silicon Drift Detector are high resolution, low-power, compact detectors used for XRF analysis world- wide. Power is supplied by the PX4, which provides both a variable Digital Pulse Shaping Amplifi er and the MCA func- tion. The Mini-X X-Ray Tube is the fi rst of its kind: a self- contained, miniature X-ray tube system, which includes the X-ray tube, power supply, control electronics and USB commu- nication to the computer. Applications for this system include RoHS/WEEE, Process Control and Alloy/Lead analysis.


Complete X-Ray Spectrometer


Silicon Drift Detectors Si-PIN Detectors


Display and Control Software and API for Windows and Windows CE


Digital Pulse Processor and MCA


Power Supplies X-ray Tube


The Amptek X-123 Complete X-Ray Spectrometer includes: 1) X-Ray Detector (Si-PIN or Super SDD) and Preamplifi er; 2) Digital Pulse Processor and MCA; and 3) Power Supply and In- terface with PC. This hand-held, low-power, high performance instrument is simple to operate. The low-cost X-123 is ideal for OEMs developing table-top or hand-held XRF analyzers.


OEM Components PROVEN PERFORMANCE


127 eV FWHM SUPER SDD


25 mm2 x 500 m


11.2 µs peaking time P/B Ratio: 8000/1


Energy (keV) Si-PIN


149 eV FWHM 6 mm2


x 500 m , this CS-1215 radial


column is truly maximising throughput at minimal floor space requirement. In general Proxcys’ CRIO-Annular columns offer a robust alternative especially where space or payload present issues in DownStream Processing.”


Circle no. 343


OEMs have made Amptek their number one choice when de- veloping hand-held and table-top instruments for XRF analysis. Amptek offers a complete line of OEM detectors, preamplifi ers, heat sinks, digital pulse processors with MCA, and power sup- plies. Also, available are the USB controlled Mini-X X-Ray Tube and the XRF-FP Quantitative Analysis software. see our web-site for further details.


Please


25.6 µs peaking time P/B Ratio: 6200/1


Energy (keV)


AMPTEK Inc. www.amptek.com


Circle no. 344


5.9 keV 55


5.9 keV


55 Fe


Detector with Preamplifi er and Heat Sink


Fe


LAB ASIA - MARCH/APRIL 2010 - CHROMATOGRAPHY & SPECTROSCOPY


Counts


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