40 Multimode Readers offer Staying Power for Biomolecular Research
Scientists at the University of Toronto, Canada, have chosen generations of Tecan microplate readers to monitor the effects of environmental or drug perturbation on molecularly barcoded yeasts. The Corey Nislow and Guri Giaever laboratories, which have recently moved to the Department of Pharmaceutical Sciences at the University of British Columbia, are responsible for monitoring the growth of large pools of barcoded yeast, simultaneously screening 6,000 mutants. Corey explained: “We first developed a workstation for this work in 2000, which consisted of four Tecan GENios™ microplate readers integrated with a multiprobe liquid handler to monitor the growth of cultures. We chose the GENios reader because it was the only instrument at the time that had a sufficient orbit to keep yeast cells well suspended and that could maintain temperature without condensation. Although this system is still in use, transfer of plates for periodic sampling is very much the rate - limiting step of this set-up, so we created a second generation system using Tecan’s Safire™ reader and a Freedom EVO®
200 liquid handling workstation equipped with six shaking incubators.”
“We didn’t just ‘settle on’ Tecan, we purposely selected the Company, and so did all of our collaborators, who loved the growth curves they saw from our work. We have remained with Tecan and, between the Toronto site and a sister laboratory at Stanford University, we now have 24 GENios systems, all of which are still running! The flexibility of the Tecan systems is a big advantage, and our third generation system at the University of British Columbia, with two Infinite® further increase our capabilities,” concluded Corey.
series readers and twelve shaking incubators, will MORE INFO. 137
Portable Balance Delivers Unparalleled Precision and Value For Lab Applications Durable and nimble, the Highland®
portable precision balance from Adam Equipment is packed with built-in, practical features that make laboratory weighing easier and
more efficient than other balances in its category. Highland’s innovative design elevates it to a level of durability and functionality previously seen only in more expensive balances. Its internal ShockProtect®
feature helps
prevent damage from overloads if heavy items are placed on the balance. The standard, patented HandiCal® is an intuitive feature that offers quick and effortless calibration without using external weights, ensuring consistent measurements each time.
All Highland models come equipped with a built-in security slot for a Kensington-type lock and cable. A sealed, colour-coded keypad with large, backlit LCD and dual tare keys make operation smooth and simple. The Highland includes features such as capacity tracker, zero tracking and full-range tare, along with RS-232 and USB interfaces to facilitate speedy communication with computers and printers. A rechargeable battery, removable draft shield, adjustable feet, levelling bubble, stainless steel pan and a weigh-below hook for density and specific gravity measurements are standard on the balance. Available in eight models, the Highland boasts capacities from 120g to 3000g and up to 15 different units of measure.
MORE INFO. 138
New Rheometer Covers all Rheological Applications
Anton Paar introduces a rheometry revolution: MCR 702 with modular TwinDrive™ technology. This is the world’s first rheometer to cover all possible rheological applications, with an accuracy of 1 nNm and features like the IsoLign Piezo flange, offering measuring gap control down to an unprecedented size of 10nm.
Anton Paar’s TwinDriveTM technology combines two powerful synchronous EC motor units in a modular setup: the upper EC motor in the rheometer is permanent; the lower EC motor can be extracted and integrated at will. Due to the EC motor's renowned dynamism and precision, users have several options of how to employ these motor units to fit their specific requirements.
In this mode, the rheometer employs both EC motors as drive units and torque transducers, optionally rotating in opposite or parallel directions. Doubled EC motors extend the scope of testing options, e.g. with optional counter-rotation for enhanced rheo-microscopy. MCR 702 TwinDrive™ can be operated with both motors’ maximum shear rates combined and is optionally employed for extensional rheology applications or tests with parallel rotation at different speeds.
The 2EC mode also enables users to employ the motors in a more synchronised fashion, making ‘different demands’ on each of them. Because of the EC motors’ outstanding precision, one motor is easily brought to a standstill and operated solely as a torque transducer, while the other motor is used as a drive unit only. This turns MCR 702 into the best available separate motor transducer rheometer for rotational and oscillatory tests, at the unprecedented torques and normal forces offered by Anton Paar’s EC motors only.
In the EC mode, the lower motor unit is easily removed in accordance with individual application needs. This procedure is fully supported by ToolmasterTM, the MCR’s automatic tool recognition and configuration system. After the extraction of the lower motor, the instrument can be operated as a single-drive rheometer, making the most of the single EC motor’s TruStrainTM capability and enabling ‘classic’ stress-controlled tests. The EC mode opens MCR 702 up to the wide variety of custom-tailored temperature devices and application-specific accessories the MCR series is famous for.
MORE INFO. 139
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INTERNATIONAL LABMATE - MARCH 2013
The Laboratory World at Your Fingertips
with full Video Content in every Labmate issue
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