Chromatography 15 Release of Application Note for Analysis of Microcystin Toxin in Drinking Water
Bruker has released an Application Note detailing the development for analysis of microcystins in drinking water, by direct injection on the recently introduced EVOQ EliteTM liquid chromatography mass spectrometer triple quadrupole(LC-MS/MS). Microcystins (MCs) are cyclic heptapeptides produced by cyanobacteria in lakes and reservoirs that experience seasonal algal bloom. MCs are toxic to animals and humans, with widespread adoption of the World Health Organization’s (WHO) guidelines of 1µg/L in drinking water. Using the EVOQ Elite LC-MS, Bruker has developed the method for the detection and quantification of three common MCs (MC-LR, -YR, -RR) in drinking water to ensure its safety. The Application Note is available to download at
http://bit.ly/BCA456.
The Application Note explores the high sensitivity of the EVOQ Elite LC-MS/MS, in detecting parts per billion (ppb) concentrations of MCs. Water containing three common cyanobacterial toxins was directly injected into the EVOQ. The MCs were examined over three orders of dynamic range, from 50 ppb to 0.05 ppb. The EVOQ proved sensitive to detect 0.00 ppb of MCs with good repeatability of <10% relative standard deviation (RSD), far exceeding the guideline set by the WHO of 1µ/L, demonstrating that the EVOQ Elite can easily be utilised to ensure safe levels of MCs in drinking water.
Meredith Conoley, Bruker CAM Marketing Director, explained that “the EVOQ Elite is designed to deliver game-changing performance for laboratories involved in high throughput quantitation. Innovations in hardware, including the revolutionary Active Exhaust and Orifice Interface, have contributed to an LC-MS/MS of exceptional sensitivity, while the EVOQ’s IQ Dual Ion Funnel, VIP-HESI and the new PACER software make it user-friendly and cost-effective.” Conoley went on to say that “with its sustained high performance, the EVOQ Elite offers advantages to any lab conducting routine analysis of water quality, as well as environmental monitoring and food testing.”
MORE INFO. 44
Parallel Sample Preparation System for HPLC Vials
Porvair Sciences has announced a new version of its MiniVap™ Blowdown Evaporator able to quickly and safely remove solvent from up to 48 vials in parallel. Made from solvent resistant black polypropylene the new MiniVap Vial Holder has been designed to accommodate up to 48 vials in a standard SLAS /ANSI format.
Incorporating advanced evaporator head technology which directly injects heated nitrogen into 48 HPLC vials simultaneously, the MiniVap removes the traditional laboratory ‘bottleneck’ of solvent evaporation from vials.
The MiniVap™ Blowdown Evaporator takes just minutes to remove volatile organic solvents from your samples collected in 24- or 96-well microplates and now HPLC vials.
Compact in design the affordably priced MiniVap™ is simple to install, operate and maintain. Install tion just requires connection to a gas supply and standard mains socket. Safety of operation is ensured as the CE marked compact unit fits into all fume cupboards.
MORE INFO. 45 ADVERTORIAL
Analysis of Nitrosamines in Malt for Beer & Whisky
In Brewing Barley undergoes a malting process, the grain if first drenched to make it germinate and then dried in kilns to capture the sugar and flavour compounds for the brewing process. The Heating in the kilns can cause the formation of carcinogenic nitrosamine compounds in the grain, these can then potentially be passed on to the final brewed product. It is therefor essential that any malt used in brewing is checked for nitrosamine levels.
The 800 Series Thermal Energy Analyser (TEA) has been an industry standard for nitrosamine analysis since its introduction thanks to its incredible sensitivity and almost infinite selectivity for nitrogen containing compounds. The 800 Series TEA can be interfaced with most common GCs.
For further information visit:
www.ellutia.com/
800TEA.html MORE INFO. 46 Gas Pipeline Permeation Analyser
High-pressure pipelines are used for transporting oil and gas. It is important to test the permeation of the materials used to manufacture the pipelines for a number of reasons. Firstly it is essential to test what levels compounds from the oil or gas to be transported through the pipeline permeate through the material. This helps to ensure that potential product loss and that ground contamination is kept to a minimum. It is also possible to monitor the degradation of the pipe material overtime to help ensure life expectancy of the material.
Ellutia has designed a system to perform this analysis consisting of the following main items:
• A 200 Series Gas Chromatograph (GC) fitted with Catalytic Converter (CC)/ Flame Ionisation Detector (FID) and Flame Photometric Detector (FPD)
• An automatic 6 position Gas Sampling Valve, installed in the GC Column Oven • An automatic 8 position Stream Selection Valve (only 4 positions currently used)
• 4 Mass Flow Controller units (MFC) for controlling of sample gas flow (air) to customers membrane cell
The flow of ‘sample air’ to each cell is controlled by a mass flow controller and passes over the membrane to take up any of the sample gas being tested. Each cell under test is continuously purged with air and flows to the Stream Selection Valve and hence to the Gas Sampling Valve and flushes the sample loop. At the start of the analysis, the sample in the loop is injected on to the GC and the sample gas analysed. Sulfinert tubing and/or Hastelloy C material is used wherever the sample is in contact to minimise sample adsorption.
For more information visit:
www.ellutia.com/
GasPipeline.html MORE INFO. 47
Brewing Analysis Solutions Systems to Analyse
Beer, Wine, Cider & Spirits for Flavour & Off Flavour Compounds
Nitrosamines formed in Malting Processes Online Process Monitoring Systems
Acetaldehyde NDMA
Chromatography Solutions NDPA Tel: 0049 (0)561 4000430 Fax: 0049 (0)561 4000429 Web:
www.ellutia.com Email:
info@ellutia.com MORE INFO. 48
Ethanol Propanol
Methanol
Diacetyl TCA
INTERNATIONAL LABMATE - MARCH 2013
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