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49 References


1. Gershenzon J, McCaskill D, Rajaonarivony JIM, Mihaliak C, Karp F, Croteau R (1992) Isolation of secretory cells from plant glandular trichomes and their use in biosynthetic studies of monoterpenes and other gland products. Anal Biochem 200:130–138.


2. Perrotin-Brunel, H.; Perez, P. C.; van Roosmalen, M. J. E.; van Spronsen, J.; Witkamp, G. J.; Peters, C. J.Solubility of Delta(9)-tetrahydrocannabinol in supercritical carbon dioxide: Experiments and modeling J. Supercrit. Fluids 2010, 52, 6–10 DOI:10.1016/j.supflu.2009.12.001


3. McPartland JM, Russo EB (2001). Cannabis and cannabis extracts: greater than the sum of their parts? J Cannabis Therapeutics 1: 103–132.


4. Aizpurua-Olaizola O, Soydaner U, Ozturk E, Schibano D, Simsir Y, Navarro P, et al. Evolution of the cannabinoid and terpene content during the growth of Cannabis sativa plants from different chemo-types. Journal of Natural Products. 2016; 97: 324–331.


5. McGraw, G. W.; Hemingway, R. W.; Ingram, L. L.; Canady, C. S.; McGraw, W. B. Thermal degradation of terpenes: Camphene, Delta(3)-carene, limonene, and alpha- terpinene Environ. Sci. Technol. 1999,


33,4029– 4033 DOI: 10.1021/es9810641


6. Rovetto, Laura & V. Aieta, Niccolo. (2017). Supercritical carbon dioxide extraction of cannabinoids from Cannabis sativa L. plant material. The Journal of Supercritical Fluids. . 10.1016/j.supflu.2017.03.014.


7. Waters. “Investigator SFC System.” Power of analytical method development and small-Scale purification : Waters, www.waters.com/waters/en_US/Power- of-analytical-method-development- and-small-scale purification/nav. htm?cid=10145751&locale=en_US.


HPLC 2018, the 47th International Symposium and Exhibit on High Performance Liquid Phase Separations and Related Techniques: July 29 - August 2


Leading the way to ensure the Separation Sciences remain a powerful analytical tool, HPLC 2018 will be held at the Washington Marriott Wardman Park, Washington, DC 20008, USA.


Professor Norman Dovichi, HPLC2018 Chairman


Are you interested in mass spectrometry, chromatography, or electrophoresis? Are you solving complex analytical problems? Are you looking for a conference with strong scientific content, a robust program, presentations by world renowned experts, lectures by young scientists, courses offering


great training opportunities, tutorials, panel discussions, vendor technical workshops, best poster competition and a major exposition showcasing new product launches and innovative products? Mark your calendar to attend HPLC 2018 Washington, DC, the largest, widely recognised international conference in the world devoted to advances in separation technologies!


Join us for a dynamic and innovative program packed with papers on column and stationary phase technology, interface to mass spectrometry, microfluidic systems, capillary electrophoresis, LCxLC, QA&QC methods, QbD in separations and application to real world problems. A special emphasis in applications will be on bioanalysis including: pharmaceuticals, antibody-drug conjugates, antibody characterisation, continuous flow manufacturing, biotechnology, proteins and proteomics, glycomics, metabolomics and lipidomics, food and nutrition, well-characterised biologicals, biofuels, environment, toxicology and more!


Plenary Speakers


• Alberto Cavazzini, Professor, University of Ferrara • Stacey Ma, Vice President, Head of IMP Quality, F. Hoffmann-La Roche Ltd. • Koji Otsuka, Professor and Department Chair, Kyoto University


• Richard D. Smith, Battelle Fellow and Chief Scientist, Pacific Northwest National Laboratory


• Mary J. Wirth, W. Brooks Fortune Distinguished Professor, Purdue University


This list of Confirmed Keynote and Invited Speakers continues to grow! Experts will present on a wide range of topics related to all aspects of liquid-phase separation science and analysis, including mass spectrometry, chromatography, and electrophoresis.


Great Training Opportunities through Practical Short Courses


Two-dimensional Liquid Chromatography: Principles, Instrumentation, Method Development and Applications.


Chromatography in the Analysis and Characterisation of Protein Therapeutic Drugs.


LC-MS and LC-MS/MS of Small Molecules. HPLC/UHPLC Method Development.


Contributions of LC and LC/MS to Characterize Protein Glycosylation. Introduction to Capillary Liquid Chromatography. HPLC Operation, Maintenance and Troubleshooting.


The Essential Roles of Separation Science in Mass Spectrometry-Based Metabolomics for Biomarker Discovery in Clinical Research. Cannabis Analysis.


Free Tutorials will be presented by experts who will give 45-60 minute presentations on topics with more background than might be found in a typical 20 minute talk.


A Major Exhibition will be showcasing the industry’s latest and greatest in instrumentation, software, tools, accessories and consumables covering all areas of liquid-phase separation science and related techniques. This major exhibition offers opportunities to view new product launches, to check out innovative products, to explore ground-breaking technologies, and to discuss challenges and solutions with experts in the booths.


Key Dates & Deadlines


February 21, 2018 -- deadline for oral abstract submissions March 31, 2018 -- early-bird registration at the lowest fees April 20, 2018 -- preliminary program posted online


April 30, 2018 -- deadline to submit poster abstracts in competition for poster awards


May 31, 2018 -- deadline to submit poster abstracts for inclusion in the final printed program


Learn more at HPLC2018.org


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