8 February / March 2018 Separation and Characterisation of Complex Charged Molecules
The EAF2000 from Postnova Analytics is an innovative new simultaneous Electrical and Asymmetrical Flow Field Flow Fractionation (EAF4) system designed to enhance separation and characterisation of biopharmaceutical, environmental and nanomaterials.
EAF4 technology uniquely combines the principle of Electrical and Asymmetrical Flow FFF in just one system. In an EAF2000 system, Electrical and Cross Flow Fields are applied simultaneously across the FFF channel enabling separations by particle size and particle charge based on
electrophoretic mobility. Combining these two powerful separation techniques in a single platform opens the door to characterising complex proteins, antibodies and viruses as well as environmental and charged nanoparticles or polymers that have proven intractable to other techniques.
The EAF2000 system integrates Postnova’s market-leading AF2000 Asymmetrical Flow FFF system, with an additional Electrical FFF module, special EAF4 channel and easy-to-use software platform. The new PN2410 Electrical FFF module is used to establish and precisely control the Electric Field allowing constant and reproducible separation conditions. This module and the EAF4 channel are connected to a standard AF2000 Flow FFF system which is controlled by the NovaFFF – EAF4 software which provides constant current operation and data evaluation for electrophoretic mobility calculation.
Modular in design, the AF2000 FFF system incorporates the combined experience, expertise and technological advances from Postnova Analytics’ nearly two decades of leadership in FFF. Incorporating a range of FFF modules in a single integrated system to provide universal separation, the AF2000 offers more flexibility, better performance and more robust results than any system before. The AF2000 FFF system is available with a wide range of add-on modules, extra options and special FFF detectors, such as Refractive Index (RI), Multi-Angle Light Scattering (MALS) and Dynamic Light Scattering (DLS). All Postnova FFF modules and detectors have been especially developed for FFF and are perfectly optimised not only for the use with the AF2000 but also for easy interfacing with high-end detection technologies from other suppliers that may already be at use in your laboratory.
For further information on the EAF2000 system please visit
www.postnova.com/ overview_759.html.
Complete Application Guide Helps Users
Select the best Column and Method Conditions Industry-leading stationary phases from Advanced Chromatography Technologies are the best choice for the development of your method. The ACE Complete Applications guide groups together over 320 HPLC/UHPLC applications from the worlds of pharmaceutical, environmental, food and beverage, forensics, clinical, and biomolecule analysis to help you make the best choice of ACE phase and method conditions for a successful separation.
With applications from both the Advanced Chromatography Technologies R&D team and submissions from chromatographers worldwide, the ACE Applications Guide is up to date with the best practices and methods from the cutting edge of research.
Furthermore, you can contribute to ACE applications! Contact us to discuss your ACE HPLC/UHPLC application and whether it can be added to our applications database. If the application is suitable and with our prior written agreement, we will send you a free HPLC/UHPLC analytical column as a thank you for helping your chromatography colleagues around the world. ACE applications data in the proteomics and biopharmaceutical sectors are particularly welcomed at this time.
To request your free copy of the ACE Complete Applications Guide now or for more information on any ACE product, contact
info@ace-hplc.com.
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