That Promote Longevity A
re there any supplements that have evidence showing that they promote longevity and/or actually help you look younger? There is intriguing evidence on some supple-
ments that show anti-aging effects. However, human studies on this are hard to find. Most of the evidence we have is on animals and/or cell cultures. In the near future we will begin to see stud- ies in humans. In order to help separate marketing hype and factual evidence
in regards to longevity supplements we should first get an idea of how we age in the first place. Knowing the different biological mechanisms of aging, along with parsing through the evidence, we can get an idea of what supplements probably have an anti- aging effect. Let’s first get a definition of what aging is to better understand
how nutraceuticals can play a role in reversing, stopping or at least, slowing down, the process. Aging is simply the progressive accumulation of damage in
the body over time leading ultimately to disease and eventually, death. If one lives long enough, aging will eventually kill you. After all, as far as we know, no human or any other organism has
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survived aging. It is the number one cause of disease and death. So if we can at least slow down the aging process then we are also significantly reducing the risk of all chronic disease and known diseases of aging (cancer, diabetes, heart disease, demen- tia, osteoporosis, etc.) So the known mechanisms of biological aging are the fol-
lowing: Glycation - Glycation is a biochemical reaction between
sugars, such as glucose, and proteins, lipids or nucleic acids in the body. Sugars bind to proteins, lipids, or nucleic acids so that they work less efficiently in the body. It is analogous to rusting of, say, a car engine.
Chronic Inflammation - Inflammation, when chronic, is a
slow, insidious, and persistent destruction of tissue due to an injuring agent (either exogenous or endogenous) where the body cannot keep up in repairing itself. Most chronic diseases are due in part to chronic inflammation.
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5 Supplements
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