26 ANALYTICAL AND LABORATORY EQUIPMENT
Such a matrix opens up numerous new possibilities. In this way, the influence of the physical environment (stiffness and architecture) on stem cell differentiation or cell migration can be investigated.
Forces can be measured and reactions to various stimuli can be observed and analysed. Te results include knowledge regarding tissue regeneration or the influence of active pharmaceutical ingredients on wound healing, for example.
‘Writing’ with a laser pen How structures are fabricated is not trivial at all, however, the principle is easy to understand: as a result of strongly focusing ultra-short laser pulses into the photosensitive and biologically compatible polymer, the polymer is exposed to light in the focus through a nonlinear process.
Comparable to a pen that is guided in three dimensions, the laser beam writes into the material along any desired paths. Line widths from
“A typical area of application for 3D laser lithography respectively 3D printing is also the creation of three-dimensional structures for cell biology.”
Fig. 2. The influence of the physical environment (stiffness and architecture) on stem cell differentiation or cell migration can be investigated with tailored cell scaffolds.
Photo: courtesy of Prof. Dr. Martin Bastmeyer, Benjamin Richter, KIT.
several micrometers down to 150 nm are achieved in this way.
However, a high precision with the 3D trajectory writing mode can only
be realised when the positioning is correspondingly precise. During the writing process, the laser and focus remains fixed and the workpiece has to be moved according to the
Find out where you can see our latest
TECHNOLOGY
DEMONSTRATIONS in Europe. Go to the PSL
online events calendar
www.powdersystems.com
Eurolab-Micro-horz
advert.indd 1
For more information ✔ at
www.scientistlive.com/eurolab
07/11/2013 16:15:20
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68