72

nanotimes Patents

Monoether derivatives of diols, whose OH groups are located in the 2 position of carbon atoms with π-electron pairs

Inventors: Prof. Dr. Peter R. Schreiner, Hartmut Schwertfeger

Abstract: The invention relates to monoetherified diols of compounds wherein the hydroxy groups are located in the 2 position to carbon atoms with π-electron pairs and methods for producing said functionalised diols. The protective group is a –CR1R2 group, in which R1 and R2 are alkyl groups, and the protective group contains at least one halogen atom. The mo- noetherified diols according to the present invention are produced by reacting the diol with a halogenated alcohol CHOR1R2 in the presence of a catalyst acid. Suitable catalyst acids are Lewis or Bronsted acids.

The monoetherified diols allow for the targeted production of further derivatives of diols such as, for instance, the corresponding amino alcohols and amino carboxylic acids. The amino, hydroxyl, and carboxylic groups thus obtained can be converted into many other functional groups.

Contact: TransMIT GmbH, Dr. Kerstin Lischka, Kerkrader Str. 3, D-35394 Giessen, Germany, Phone: +49-(0)641- 94364-25: http://www.transmit.de

http://www.hipo-online.de/files/Synopsis_Benzylic_Mo- noethers_TM306_EN2_280410.pdf

10-05/06 :: May/June 2010

Monoetherified Diols of Diamondoids

Inventors: Prof. Dr. Peter R. Schreiner, Hartmut Schwertfeger

Abstract: The invention relates to functionalised diols of dia- mondoids in which one of the two hydroxy groups is masked by a protective group, and to methods for producing said functionalised diols. The protective group is a –CR1R2 group, in which R1 und R2 are al- kyl groups, and the protective group contains at least one halogen atom. The monoethers of the diamon- doid diols are produced by reacting the diamondoid diol with a halogenated alcohol CHOR1R2 in the presence of a catalyst acid. Suitable catalyst acids are Lewis or Bronsted acids.

The monoetherified diols allow for the targeted pro- duction of derivatives of the diamondoids such as, for instance, the corresponding amino alcohols and amino carboxylic acids. The amino, hydroxy and car- boxylic groups of the diamondoids can be converted into many other functional groups.