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ANALYTICAL AND LABORATORY EQUIPMENT


The joint project speeds up the process of antibody discovery


I PARTNERSHIP YIELDSMPRESSIVE RESULTS A


Scientists use robots to test cells by the billion


n automated primary antibody screening workcell for early stage development of potential new treatments for central nervous system and immunology disorders has been designed and constructed for UCB by Peak Analysis and Automation (PAA). Built around a Mitsubishi Electric robot, the workcell speeds up the process of antibody discovery by allowing the screening of billions of antibody producing B cells.


UCB is a multinational biopharmaceutical company headquartered


in Brussels, Belgium, that focuses primarily on the R&D of neurological and immune system related medications. T e company selected PAA for the development of an automated solution for vital cell screening processes that would not have been practical to achieve manually. PAA designs automated workcells for the pharmaceutical, biotechnology, healthcare and genomic research industries.


DESIRABLE PROPERTIES To become a therapeutic candidate an antibody is required to have many


desirable properties. As more is understood about the biochemical and biophysical properties of antibodies, so the list of desirable properties becomes longer. T is quest for desirable properties produces more challenges for the area of antibody discovery; more antibodies need to be screened, tested and assessed, to allow the selection of the most suitable antibodies to progress. T e process is underpinned by the careful design and selection of appropriate primary and secondary screening assay.


www.scientistlive.com 13


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