Laboratory Products 59 Enhancing flow chemistry with CSTR cascade integration


Vapourtec has unveiled a new continuous stirred tank reactor (CSTR) designed to enhance continuous process synthesis, offering compatibility with their renowned flow chemistry systems. This innovative CSTR can be integrated into R-Series and E-Series flow chemistry platforms, significantly expanding their capabilities.


The CSTR cascade system allows for the integration of up to eight reactors within an R-Series flow chemistry system, such as two R4 modules, making it ideal for managing flow reactions that involve both solids and liquids. It operates at pressures of up to 5.0 bar and provides a reactor volume range from 5 ml to 40 ml, with precise temperature control from -10°C to +150°C.


For the entry-level E-Series flow chemistry system, the option to include up to two CSTRs is available, offering enhanced versatility in this system. This easily maintainable system prioritises safety and precision, offering stirring speeds ranging from 100rpm to 1200rpm and featuring a built-in burst disc, with an optional protective screen for added safety.


Additionally, Vapourtec provides the choice of incorporating a photochemical CSTR, which uses LED light sources spanning from 365nm to 700nm. The design of the CSTR is a result of close collaboration with leading flow chemists from both industry and academia.


Dr. Manuel Nuño of Vapourtec emphasized the innovative approach, stating: “CSTRs have a well-established presence in chemical synthesis, but our goal was to adapt and optimise them for flow chemistry, ensuring seamless integration with our continuous process systems. The ability to create an eight-reactor cascade configuration significantly improves residence time distribution (RTD) control, allowing for the separation of reaction products from starting materials and precise management of RTDs. With tailored settings for stirring speeds and temperatures in each individual CSTR, this system provides enhanced control and accuracy, leading to more precise outcomes.”


Established in 2003 and headquartered near Cambridge, UK, Vapourtec’s flow chemistry systems have played a pivotal role in the development of novel synthetic pathways for critical therapeutics, including drugs such as Tamoxifen for breast cancer, Artemisinin for malaria treatment, and peptide drugs for type 2 diabetes management.


More information online: ilmt.co/PL/vAVA 61379pr@reply-direct.com


Autoclaves for large load sterilisation


The popularity of Priorclave steam and water jacketed rectangular chamber autoclaves is due to their exceptionally large, sterilising chamber. It makes them eminently suitable for laboratories undertaking high-volume throughputs or frequently tasked with handling taller and bulkier items. Their design enables them to deliver both faster sterilising processes and drier loads more quickly and reliably.


Current models include a choice of six chambers capacities from 230 to 350L (two hand wheels) and 400 to 700L (three hand wheels). They are part of the recently extended range of BASE, SMART and PERFORMANCE models. It gives customers more choice of standard rectangular chamber laboratory and research grade autoclaves, incorporating more features and benefits.


All models are fitted with a large hand-wheel closure system for easy safe opening/closing of the rigid robust hinged door. An inherent design feature is the fitting of thermal and pressure locks to the lower hand-wheel. This prevents door opening at load temperature above 80°C and pressures above 0.2 bar, thus averting potential accidents through discharge of hot pressurised steam.


The build quality and performance of Priorclave rectangular front-loading autoclaves is unquestionable - durable and dependable. They incorporate epoxy coated panels and frame members treated with an anti-bacterial agent that is highly effective and a permanent treatment for control of harmful bacteria. It makes surfaces cleaner, more hygienic and provides a durable lifelong protection against the threat of cross contamination. This coating is proven to reduce bacterial growth by up to 99.99% and is highly effective against MRSA, E- coli, Listeria, Legionella, Campylobacter, Salmonella, Pseudomonas and over fifty other species.


More information online: ilmt.co/PL/jMjO 61817pr@reply-direct.com


For sale: Established electrochemical devices manufacturing business


Weiss Research announces the availability of its well-established electrochemical devices manufacturer for over 20 years. Specialising in the production of Laboratory and Industrial water testing sensors, including pH, ORP, and Ion-Selective Electrodes (ISEs), the company offers a range of equipment and machinery for the production process. This sale encompasses all necessary raw materials, such as glass/epoxy tubing and chemical components.


Included in the package are the proprietary formulas for all products, including the highly regarded glass formula. To facilitate a smooth transition, Weiss Research is also providing lists of current customers, vendors, and potential clients compiled over the past decade.


Interested parties looking to acquire this reputable company are invited to contact Weiss Research at gzw189@gmail.com. 61899pr@reply-direct.com


New-generation laboratory balances


METTLER TOLEDO announces the launch of four new laboratory balance lines. Starting today, laboratories from large enterprises, medium-sized companies and startups worldwide will have a more comprehensive and superior selection of balances to ensure accurate weighing. Customers will benefit from a broad range of balance models that meet the needs of every user, industry and workplace, from advanced weighing requirements to the most essential weighing needs. The new portfolio is engineered for enhanced user experience, designed with sustainability in mind and built with the highest quality materials for trusted, long-lasting performance.


The MX balances boast weighing performance, effortless data management and user-friendliness. With innovative engineering, these balances provide an ergonomic weighing experience and satisfy advanced weighing requirements. Highly intuitive and with a multitude of smart features, such as ErgoDoors, SmartPan, StatusLight, LevelControl and advanced routine testing functions, these balances simplify your weighing tasks. To easily comply with GxP regulations, they offer user management and activity log traceability.


MR balances deliver consistently accurate results even in the harshest weighing environments. Thanks to their robust construction, these balances are the perfect choice whether you weigh in a busy lab or the challenging conditions of a production setting. A range of built-in applications and connectivity options make MR balances highly versatile.


To make every day weighing easy, MA balances are designed with a focus on valuable, practical features, and they deliver quality without compromise. Touch control on a bright LCD screen, simple menus, guided applications and easy result documentation make weighing a breeze. These balances are also available in a compact portable design with battery operation that saves valuable space on your workbench and enables you to easily transport your balance.


With the LA balances, you can experience affordable quality with all the basic functions you need for essential weighing tasks. LA balances feature a bright LCD display for optimal reading in all conditions. With an RS232 interface, you can connect to a printer, secondary display, or other device. Each balance has three integrated applications (weighing, dynamic weighing and piece counting).


More information online: ilmt.co/PL/5B43 61902pr@reply-direct.com


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