analytica trade fair: The whole world of the laboratory in the USA


Olesik from Ohio State University on ‘Enhanced Fluidity Liquid Chromatography-Mass Spectrometric Analyses of Proteins, Oligosaccharides, and Oligonucleotides’.


Albert Sickmann, research associate at the internationally renowned Leibniz Institute, will talk about ‘Population based proteomics: Platelet data for elucidating mechanisms of cardiovascular diseases’.


On the second day, 10 September, the topic of proteomics will be discussed in the session dealing with chromatography and spectroscopy.


An overview of the entire scientifi c conference program of analytica USA can be found here: ilmt.co/PL/DG09


All the leading manufacturers will be at analytica USA Credit: Messe München GmbH.


From 10 to 12 September 2025, analytica will open its doors in the USA for the fi rst time. An estimated 250 exhibitors will present a comprehensive range of products and services for the world of laboratories in industry and science at the Columbus, Ohio location. The concept of the trade fair will be new and unique for the US.


A two-day scientifi c conference covering the topics of proteomics, chromatography and spectroscopy will be held as part of the trade fair. The ‘Session One Health’, will take place on 10 September and will include a presentation by Susan


Whether it’s classic analytical methods such as chromatography, spectroscopy or particle analysis or balances, weighing accessories and microfl uidics, all the leading manufacturers will be there. Among others, A & D Weighing, Bruker, Jasco, Shimadzu, Sartorius, Ohaus, Mettler Toledo, Thermo, Waters, Perkin Elmer, Malvern and many other exhibitors will present their latest innovations at analytica USA.


All exhibitors at a glance can be found at ilmt.co/PL/WwEm


analytica is the go-to source for information on all topics vital to the modern laboratory.


Managers will learn about the laboratory of the future and digital networking at analytica USA. Laboratory users who carry out daily sample preparation and routine analysis will fi nd up-to-date solutions for their processes in the live presentations.


Susanne Grödl, Exhibition Director analytica USA. Credit: Messe München GmbH


For all laboratory users and decision-makers, personal safety in the laboratory is the top priority. Analytica’s special experimental show will provide the crucial tips you need to avoid accidents.


The program of the special shows at a glance at ilmt.co/PL/ew0X


Register for a visitor ticket at ilmt.co/PL/ED06 More information online: ilmt.co/PL/wY3E


64918pr@reply-direct.com New insights into how ticks control deadly SFTS virus


A team of scientists from the Liverpool School of Tropical Medicine has revealed key mechanisms by which ticks resist infection from severe fever with thrombocytopenia syndrome virus (SFTSV), a dangerous virus spreading in parts of East Asia.


Their research [1], published in Nature Communications, focused on the tick species Rhipicephalus microplus, examining how its cells respond at the molecular level to SFTSV. The virus can cause severe illness and death in humans, and no approved treatment or vaccine exists. As climate change expands tick populations, understanding their role in disease spread is increasingly urgent.


By applying advanced gene and protein analysis techniques, the researchers identifi ed two proteins - UPF1 and DHX9 - that act to limit viral replication inside tick cells. This suggests ticks have active antiviral defences, not just passive virus carriers.


Professor Alain Kohl from LSTM explained: “Ticks possess sophisticated systems to detect and control viruses, which could be targeted to break the chain of infection.”


Lead author Dr Marine Petit added: “Our fi ndings challenge the notion that ticks are simply passive hosts. Instead, they use conserved proteins as antiviral defenders, opening new avenues for preventing virus transmission.”


The study also expanded knowledge of tick biology by identifying hundreds of previously unknown proteins, laying groundwork for further research into controlling tick-borne diseases.


This collaborative project included researchers from the University of Surrey, University of Glasgow, University of Liverpool, and University of Dundee.


More information online: ilmt.co/PL/Mw9X


1. Multi-omics analysis of SFTS virus infection in Rhipicephalus microplus cells reveals antiviral tick factors published in Nature Communications


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Visual breakthrough targets breast cancer spread


invisible cellular signals in real time, opening new avenues to limit cancer dissemination.


Led by Professor Johanna Ivaska and Dr James Conway, the team focused on understanding how breast cancer cells transition from a pre-malignant state (ductal carcinoma in situ, DCIS) to invasive ductal carcinoma (IDC), a progression associated with poorer patient outcomes and incurable metastatic disease.


Cancer cells degrading their surrounding matrix. Microscopy image of invasive breast cancer cells (labelled in yellow) degrading their underlying extracellular matrix (labelled gelatin in red, degraded areas appear as black holes). Credit: Omkar Joshi, Turku Bioscience Centre, University of Turku. Scale bar, 20µm


Researchers at the University of Turku, Finland, have created an innovative fl uorescent probe that visualises the complex signalling events driving breast cancer cell movement during metastasis. This breakthrough tool, named Illusia, allows scientists to observe previously


“Cell signalling controls vital processes such as growth and movement, but tracking these signals inside living cells has been a major challenge,” said Dr Conway. “Illusia is designed to illuminate these dynamic signals, enabling us to see how cancer cells respond and migrate.”


Their research [1] identifi ed the protein phosphatase Shp2 as a crucial regulator that controls how cancer cells interact with their surroundings during invasion. Notably, drugs already in clinical trials targeting Shp2 in other cancers show promise to also block breast cancer spread, providing hope for new treatment strategies.


“Metastasis relies on cancer cells moving from the primary tumour to distant organs, yet no current therapies effectively block this migration,” explained Professor Ivaska. “Our fi ndings highlight a potential therapeutic


target that could change that.”


Beyond breast cancer, this discovery offers insights into the broader mechanisms of cancer cell invasion across solid tumours.


Illusia’s name was inspired by a Finnish folklore about a fairy from the rainbow, refl ecting the colourful signals the probe reveals and the team’s quest for better cancer treatments.


Professor Johanna Ivaska leads a research group within InFLAMES Flagship, a collaborative initiative between the University of Turku and Åbo Akademi University in Finland. The programme focuses on discovering new drug targets and advancing personalised therapies through partnerships with biotechnology and pharmaceutical companies. InFLAMES is supported by the Research Council of Finland as part of its fl agship programme.


More information online: ilmt.co/PL/0Zdn


1. Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells published in Nature Cell Biology


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