Laboratory Products 33 Platform enhances perfusion bioprocessing effi ciency and scalability
Celonic Group, a leading Swiss-based contract development and manufacturing organisation (CDMO), has integrated Merck’s Breez™ micro-bioreactor platform into its process development workfl ow. This strategic integration enhances Celonic’s expertise in monoclonal antibody (mAb) development and manufacturing, enabling highly effi cient, scalable perfusion-based bioprocessing from early-stage development to commercial-scale production.
The Breez™ 2 mL micro-bioreactor platform is an automated, functionally closed, continuous perfusion cell culture system. By leveraging this advanced technology, Celonic is optimising upstream processes to accelerate product development, reduce the cost of goods per gram, and signifi cantly improve operational effi ciency in biologics production.
“This collaboration marks a pivotal moment in our commitment to advancing bioprocessing solutions,” said Samanta Cimitan, PhD, CEO of Celonic Group. “The Breez™ platform enables us to scale our production capabilities, enhance productivity, and reduce costs, benefi ting both our clients and the patients who rely on these biologics.”
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Advanced water quality testing solutions
UV LED system improves fl uorescent detection in water testing
IDEXX, a world leader in water microbiology testing, has launched the UV Viewer PLUS to improve the process of result interpretation when using IDEXX fluorescing tests. When samples are tested using the Colilert®
, Enterolert® , Pseudalert®
results of contamination after incubation may be indicated through fluorescence. Using the new UV Viewer PLUS will streamline and accelerate the interpretation process for laboratory personnel and operators.
The UV Viewer PLUS has been designed to block out greater levels of ambient light than traditional viewing cabinets and, for samples being tested using the IDEXX Quanti-Tray®
Bluephage SL, a leader in microbiological water testing, has introduced two innovative product lines to enhance laboratory effi ciency and water quality testing standards. These additions reinforce Bluephage’s commitment to delivering advanced, customer-centric solutions for water analysis worldwide.
The company has updated its Positive Control Kits, now available in two specialised formats: BP1626a and BP1626b. These kits, designed for coliphage enumeration, now contain 25 units per box - fi ve more than the previous version - offering better value and fl exibility. Laboratories can now purchase these controls separately, optimising inventory management.
The BP1626a kit is tailored for use with the Easy Kit BP1601 (1 ml samples), while BP1626b is optimised for the Easy Kit BP1604 (100 ml samples). Positive controls play a crucial role in ensuring accuracy and reliability in coliphage testing by introducing a known quantity of the φX174 bacteriophage, a global reference for detecting somatic coliphages. These kits comply with ISO 10705-2, the international standard for coliphage enumeration.
Bluephage is also launching GR8FHDT and GR8FHD, fi lterable formats of the GR8 somatic coliphage, designed to validate bacteriophage concentration in water testing. These products are compatible with Bluephage’s Rapid Kits (BPF- SE, BPF-SPA) and Easy Kits (BP1601, BP1604) and comply with ISO 10705-3, the key standard for bacteriophage concentration.
Bacteriophages often occur in low concentrations in water samples, making concentration methods essential for accurate detection. GR8, isolated from surface water, is an effective surrogate for environmental testing. Its fi lterable format simplifi es laboratory workfl ows while ensuring adherence to global water safety standards.
With two-year shelf lives and storage at -20°C (GR8FHDT) or -70°C (GR8FHD), these new formats provide long-term, reliable solutions for laboratories.
These new product launches highlight Bluephage’s dedication to innovation, regulatory compliance, and laboratory effi ciency in water quality testing.
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methods, the large viewing
area allows two Quanti-Trays to be read simultaneously. The unit contains multiple strips of energy- efficient long-life UV LED lights instead of traditional, mercury-containing UV bulbs, meaning the sample is surrounded by UV light from all angles.
From an environmental standpoint, LEDs consume less power than incandescent UV light sources, which also need replacing periodically and often require specialised, and costly, disposal. Additionally, the power button on the UV Viewer PLUS illuminates when the LED lights are on, reducing the chances of operators accidentally leaving the unit powered up when not in use.
IDEXX Water testing solutions deliver easy, rapid, accurate and cost-effective information on water quality to laboratories, public utilities, and facilities managers. Colilert-18 (ISO 9308-2) gives confirmed results of the presence of coliforms and E. coli in just 18 hours, and Pseudalert®
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ilmt.co/PL/qVxy 65113pr@reply-direct.com (ISO 16266-2) provides 24-hour detection of Pseudomonas aeruginosa. Enterolert offers 24 hour detection of
enterococci in a variety of water matrices – and all tests can be used to quantify the levels of bacterial contamination when used in conjunction with the IDEXX Quanti-Tray.
and other IDEXX methods, positive
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