14
Conclusions The novel confi guration of the LenS3
MALS detector features an elongated fl ow
chamber made of non-refractive inert material, associated with an improved optical bench and a green laser. This new design increases signal intensity while minimising noise, resulting in exceptional detection sensitivity.
Furthermore, with extreme angles at 10° and 170° in addition to the 90° angle, the instrument can detect angular dependence to an extremely low level to measure the lowest Rg ever reported by light scattering. The detector also takes advantage of the low angle to measure MW directly and accurately without extrapolation.
This innovative approach represents the fi rst signifi cant advancement in light scattering technologies in four decades. This will benefi t the analysis of all types of macromolecules, from biomolecules to synthetic polymers.
References 1. Kratochvil, P. Classical Light Scattering from Polymer Solutions; Elsevier: New York, 1987. 2. Abe, Fumiaki, et al., Macromolecules Vol 26 Issue 8 (1993) Pages 1884-1890
Figure 5. Molecular weight analysis of oligonucleotides (triplicate injection).
Figure 4 A&B. Light scattering of Herceptin Biosimilar.
New Technique Promises to Accelerate Materials Development for Gas Separations
In an exciting new advance, a team of scientists from Hiden Isochema Ltd and Cleveland State University have developed a new way of analysing materials for separating gases. Although gas separation using porous materials is an established technology, analytical techniques for assessing the performance of materials tend to be slow and laborious. The new Integral Mass Balance (IMB) method is faster and more accurate than existing techniques, and promises to accelerate new materials development for gas separation technology.
To demonstrate the technique, the team have made measurements on a zeolite. Zeolites are porous materials with a range of uses, perhaps most notably in washing powder, but they are also particularly good at separating and drying gases. The reported measurements relate to oxygen (O2
air, by separating O2 from N2 .
In medicine, where purifi ed O2 personal use, larger PSA O2
is widely used, this technology is vital. Whilst small-scale and portable medical O2 coronavirus crisis, where reliable O2 generators are widely available for
generators, fi lled with zeolites, have been installed at emergency fi eld hospitals constructed to cope with the current supplies have been critical for treating patients.
Now the team want to explore the technique’s range of applicability. “Having shown that the IMB method works for air separation using zeolites, we’d like to apply it to other important separations,” said Dr Darren Broom, Product Manager for Hiden Isochema. “Capturing CO2
from power plant fl ue gases, for
example, is of great interest, as this will help tackle the diffi cult and serious problem of climate change due to increasing greenhouse gas emissions.” Other future targets include separations used for natural gas upgrading and biogas purifi cation, as well as hydrogen (H2
H2 and natural gas are important for the transition to a low carbon energy future, in which fossil fuel use will be gradually phased out.
More information online:
ilmt.co/PL/5q0X 54205pr@reply-direct.com
) production and purifi cation. Both ) production from
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