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43 Reagents, Reference Materials & Laboratory Chemicals Range of Reference Standards Expanded to Include FFPE and Liquid Biopsy


Horizon Discovery Group plc has announced it has added two new sample formats to its cell-based OncoSpan reference standards for use in the development and validation of workflows for cancer diagnostic assays.


Horizon’s OncoSpan range now includes formalin-fixed, paraffin-embedded (FFPE) and cell-free DNA (cfDNA) formats for mimicking solid tumours and liquid biopsy samples, respectively, in addition to its well-established genomic DNA (gDNA) format. Its cfDNA format offers one of the largest number of variants and genes, over 380 and 152 respectively, of any characterised reference standard to help standardise liquid biopsy testing.


These cell-line derived reference standards closely mimic patient samples and offer an unlimited and reproducible resource to help ensure consistency during the establishment and validation of diagnostic assays. All three formats are delivered with batch-specific, next-generation sequencing (NGS) data, orthogonally validated by ddPCR, to allow researchers to further validate their analysis pipeline.


Paul Brooks, Head of Business Operations, Horizon Discovery said: “Horizon offers a range of premium reference standards for various molecular platforms including NGS and digital PCR. By extending our OncoSpan portfolio to include these additional sample formats, we are now able to provide more researchers working at the forefront of molecular diagnostics, with the reagents needed to suit their specific workflows. These cell- line derived standards offer significant benefits over less-commutable synthetic standards, meaning researchers can rely on our reference standards to deliver consistent results and have confidence in the performance of their diagnostic assays.”


More information online: ilmt.co/PL/5a53 52298pr@reply-direct.com


Confi dence in Compliance with UV-visible Spectroscopy CRMs


Starna Scientific is the world’s only supplier of Certified Reference Materials for UV-visible spectroscopy to be accredited to ISO 17034:2016, the international benchmark for reference material producers. Users of their CRMs can therefore be confident that compliance measurements will be to the highest possible standard and accepted by regulatory authorities worldwide. This accreditation, and the ISO/IEC 17025 accreditation of Starna’s calibration laboratory, covers a unique range of spectroscopy reference materials for wavelengths from the deep UV to the mid infra-red. Starna Green, for example, is a novel, non-toxic (REACH compliant) absorbance CRM usable from 250 nm to 650 nm and at absorbance values up to 5 A. Instrument users therefore have an the widest possible choice when selecting CRMs to match their analytical conditions, as required by the latest editions of the pharmacopoeias. The Starna range also includes references for microvolume measurements, microplates, fluorescence and life science applications.


More information online: ilmt.co/PL/GpmE 53026pr@reply-direct.com


A harmonious performance across a wide portfolio


The precise and time-critical nature of your work mean you need products you can rely on for all your demanding applications. That’s why the Supelco®


portfolio off ers a


comprehensive range of meticulously tested products and services for chromatography, spectroscopy, titration and many other analytical chemistry techniques. So for a harmonious performance across all your applications, choose Supelco®


analytical products.


For more information, please visit: SigmaAldrich.com/SuccessReplicated


Merck, the vibrant M and Supelco are trademarks of Merck KGaA, Darmstadt, Germany or its affi liates. All other trademarks are the property of their respective owners. Detailed information on trademarks is available via publicly accessible resources.


© 2020 Merck KGaA, Darmstadt, Germany and/or its affi liates. All Rights Reserved. The Life Science Business of Merck operates as MilliporeSigma in the US and Canada.


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