34 How Freeze Drying in Food Processing is Enabling Greater Efficiency and Superior Results
Freeze drying (lyophilisation) is the most widely used alternative to evaporative techniques in food processing. The process is based on ice crystal sublimation, allowing to achieve a high-quality product. The process consists in freezing the product and decreasing both pressure and temperature below the water triple point (0.01°C and 6.1 10-3 bar). The resulting sublimation at negative temperatures limits both chemical reactions and product degradation. Pre-treatments in hypertonic solutions are often carried out to better preserve the structure on freezing and drying as well as to enhance the product appearance and rehydration.
Freeze drying is beneficial for a wide range of products including fruit and vegetables, dairy, pet food, beverages, meat, fish and seafood as well as nutraceuticals (e.g. sport supplements probiotics).
Since freeze drying produces superior products, the range of potential users has grown exponentially to fulfil the request of military units and special forces during space and naval missions or in remote bases, tourism, athletes for extreme sports and expeditions, organisations such as UNESCO in places that are hit by disasters or conflicts, international humanitarian movements.
Biopharma has expanded their facilities for food freeze drying, introducing services built on a QbD approach that aim to assist in achieving the best results to meet customer requirements in terms of shelf life, appearance and physico-chemical properties. An initial characterisation of the thermal behaviour of the pre-lyophilised product is essential in order to design a tailored drying cycle. Without it, the risk is to use a freeze drying process that dries the product, but not in an efficient way, irreversibly affecting the quality. Technologies such as freeze drying microscopy (Lyostat), DTA & impedance analysis (Lyotherm) and differential scanning calorimetry (DSC) are typically used to fully understand the food thermal behaviour.
More information online:
ilmt.co/PL/MpLx 51407pr@reply-direct.com
New cGMP-Compatible Cell and Gene Therapy Manufacturing Portfolio Launched
Thermo Fisher Scientific announces the launch of an industry-leading product, compliance and services portfolio, compatible with current Good Manufacturing Practice (cGMP) and designed to enable rapid start-up of clinical and commercial cell and gene therapy manufacturing.
Developed as the first-ever all-inclusive solution to simplify and optimise the cGMP equipment installation and validation process, the Thermo Scientific Cell Therapy Systems (CTS) Series Laboratory
Equipment are comprised of a comprehensive range of key laboratory equipment routinely used in cell and gene therapy manufacturing, including biological safety cabinets, centrifuges and CO2 incubators. Each product includes a factory acceptance test documentation package comprised of operating certificates, performance specifications, user guides and technical manuals. The portfolio is also supported by high quality field compliance services, including installation setup, IQ, OQ and other support such as temperature mapping and calibration.
“Cell and gene therapy manufacturers are under increasing pressure to deliver new life-saving therapies, while challenged with complex manufacturing processes and the associated compliance requirements,” said Hugh Tansey, Senior Director, Innovation and Growth Programs for Laboratory Equipment at Thermo Fisher Scientific. “In support of cGMP, the CTS Series Laboratory Equipment have been developed to address some of the challenges our customers face every day so they can focus on what matters the most - using science to save patient lives.”
The CTS Series Laboratory Equipment are manufactured at ISO13485-certified sites and designed to meet global mechanical and electrical safety standards. The portfolio is available for sale in more than 150 countries and is supported by an extensive global service network of subject matter specialists.
More information online:
ilmt.co/PL/Ez19 52785pr@reply-direct.com
Unique Tool for Chemical Thermodynamic and Energy Release Evaluation Announced
INSPIRING SUSTAINABLE CONNECTIONS
World Forum and Leading Show for the Process Industries
ACHEMA is the global hotspot for industry experts, decision- makers and solution providers. Experience unseen technology, collaborate cross-industry and connect yourself worldwide to make an impact.
#ACHEMA21
14 – 18 June 2021 Frankfurt, Germany
Are you ready? Join now as speaker or exhibitor!
www.achema.de
ASTM’s CHETAH program is a unique tool for predicting both thermochemical properties and certain reactive chemicals hazards associated with pure chemical, a mixture of chemicals, or a chemical reaction. This is accomplished through knowledge of only the molecular structure(s) of the components involved by an implementation of Benson’s method of group additivity. CHETAH is useful for classifying materials for their ability to decompose with violence, for estimating heats of reaction or combustion, for prediction of chemical equilibrium, and for predicting lower flammable limits.
This most updated version of CHETAH Version 11.0 has an improved interface to enhance ease of use.
Various property databases have now been reviewed for consistency and accuracy. Updated thermodynamic values are provided for 20 Benson groups based on latest best values in the literature. The database for ideal gas Benson groups has been expanded and now contains 1,165 groups. It is the largest Benson group database known to exist. In all, 66 new groups have been added. 47 groups have been updated or include additional data. Entropy values were predicted and added to the database for many ideal gas Benson groups that were missing such values. This also enables Gibb’s Free Energy calculations for these groups. Output reports have been improved for clarity of presentation. It is now possible to generate pdf format reports direct from the interface as well as Microsoft Word© documents.
Aside from significant improvements from the previous version, NASA Lewis chemical equilibrium calculations are now available for the first time within CHETAH. This allows the user to predict equilibrium compositions, pressures, and temperatures of a user selected list of reactants. The extensive database of chemicals within the CHETAH databases can be used as reactant chemicals. Also, chemicals not in the databases or even in the published literature can be entered as reactants by making use of the Benson group molecular fragment database. CHETAH 11.0 uses Microsoft Access for database management and to manage the user interface. The calculation details are accomplished in the Visual Basic for Applications structure of Access and in C language. CHETAH 11 is designed to be compatible and seamless with the current versions of the Microsoft Windows operating system.
More information online:
ilmt.co/PL/pOnL 52858pr@reply-direct.com
INTERNATIONAL LABMATE - SEPTEMBER 2020
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76 |
Page 77 |
Page 78 |
Page 79 |
Page 80 |
Page 81 |
Page 82 |
Page 83 |
Page 84
