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Contents Head Office


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Michael Pattison, Chairman International Labmate Ltd.


Trevor Hopkins, Editor Chromatography Today Tel: +44 (0)7921 021378 trevor@intlabmate.com


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Editorial Review Board Tony Edge


Senior Manager (Chromatography) VWR, part of Avantor


Dr James P. Grinias


Assistant Professor of Chemistry & Biochemistry at Rowan University, Glassboro, New Jersey, United States


Dr Jonathan Crowther Senior Research Fellow


Ortho Clinical Diagnostics, United States Dr Frank P. DiSanzo


ExxonMobil Research & Engineering Analytical Science Laboratory, United States


Ray T. McClain


Associate Principal Scientist Merck & Co. , Inc., United States


Dr Lucie Nováková Associate Professor


Charles University, Faculty of Pharmacy, Hradec Králové, Czech Republic


Dr Matthew Przybyciel


Vice President and Technical Director ES Industries, United States


Professor Torgny Fornstedt Analytical Chemistry


Department of Engineering and Chemical Sciences Karlstad University, Sweden


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Rozing.com, Germany


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Published by International Labmate Ltd. Printed in the UK by The Manson Group Ltd


46 Experience and Applications of a New Portable HPLC Machine


40 µ-Pillar Array Column –


an Innovative Approach for the Separation and Characterisation of Complex Biological Samples


36 Hybrid Structures for Complex Analytical Instruments


30 New Monodense Large Pore Silica-Based Materials for the Analysis of


Biomacromolecular Compounds by Reversed- Phase Liquid Chromatography


26 Practical Impact of Dispersion on Fast Chromatographic Separations


20 Evaluation of Mixed-Mode Ion Exchange SPE for the Extraction of Opioids from


Human Urine by UHPLC-MS/MS


14 Expanding the Boundaries of Light Scattering for Macromolecules


10 Ultrahigh Sensitivity Analysis of Adeno-associated Virus (AAV) Capsid


Proteins by Sodium Dodecyl Sulphate Capillary Gel Electrophoresis


ISSN: 1752-8070


2 Foreword by Trevor Hopkins Articles


4 LC-MS Analysis of Therapeutic Oligonucleotide and Related Products A comparison of TQ and Q-TOF Systems


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