Luminescence, UV & Microplate Readers
Entry Level Reader Confi gurations to Simplify Basic Research
Tecan’s popular Infinite® 200 PRO series of multimode microplate readers has been updated to even better serve the life sciences market, with a number of new options and configurations designed to provide flexible and user-friendly solutions for entry level research applications. The proven and trusted Infinite 200 PRO microplate reader has been engineered for excellence, and has so far featured in more than 1,800 peer reviewed articles around the world. Based on further customer feedback, it is now available in six application-focused configurations, allowing researchers to choose the perfect solution for their specific needs and budget today, with the option to upgrade as requirements change.
The new, budget-friendly configurations include two single- and four multi-mode configurations for absorbance, luminescence and fluorescence detection. Together with a range of optional modules, these instruments ensure high quality results for ELISAs, nucleic acid quantification, reporter assay technologies and drug discovery applications, including HTRF® and fluorescence polarisation. This upgradable platform can help to simplify target applications and laboratory workflows, delivering performance and value to every lab, every day, for every assay.
For more information, visit
www.tecan.com/infinite200pro
42790pr@reply-direct.com New Website Enables Easier Access to Expert FISH Advice
Oxford Gene Technology has launched a new version of its Cytocell® fluorescence in situ hybridisation (FISH) probes website, designed to provide a wealth of information and advice, offer refined functionality, and be easy-to-use. Cytocell is well known for its complete and comprehensive range of FISH probes, exceptional customer support, service and expertise. In the spirit of sharing this expertise and knowledge, OGT has redeveloped the website to increase accessibility to the brand’s know-how.
Taking on board feedback from customers requesting a visual search aid, OGT has created an interactive chromosome search tool designed to be familiar to cytogeneticists and facilitate the quick and easy identification of appropriate probes. The tool provides a visual representation of the chromosome using the ISCN (International System for Human Cytogenetic Nomenclature) G-banding end users are familiar with, and uniquely, enables scrolling over the chromosome bands to pinpoint the location to be targeted by a probe. The new website also includes a redesigned probe search function, allowing users to quickly locate probes by conducting a free text search or by filtering using a comprehensive set of probe filter options. New product pages make it easy to access an increased number of resources and simpler to request samples and quotes.
A re-vamped support section includes Cytocell’s popular FISH ‘n’ Tips area, a collection of tips from Cytocell experts - soon to be opened up for contributions from end users - enabling the sharing of knowledge and best practice within the FISH community. The site now also features instructional video content including a detailed protocol video for pre-treatment of formalin fixed, paraffin embedded samples prior to FISH, a notoriously difficult step in the process. In addition, the quick-to-access FAQ section has
expanded and features question grouping by stage of the FISH process to make relevant information easy to locate.
Emma Shipstone, EVP Marketing at OGT commented, “Our Cytocell brand is already very well known for the excellent level of knowledge and support we provide customers. We wanted to expand the global reach of this to enable customers even easier access - providing them with expertise and information online, and at their fingertips, 24/7.”
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New Affordable Automated Microscope Announced
BioTek makes it even easier for laboratories to transition into automated digital microscopy with the new, fully integrated Lionheart™ LX Automated Microscope. The affordable and compact Lionheart LX offers high contrast brightfield, colour brightfield and fluorescence imaging with up to 100x air and oil immersion magnification. Users can automatically image microplates, slides, cell culture dishes and flasks with ease.
Gen5™ Microplate Reader and Imager Software controls Lionheart LX. Together they enable Augmented Microscopy™ for fully automated image capture, processing and analysis. User-friendly automated features include autofocus, auto exposure and auto-LED intensity, and the ocular-free hardware eliminates the ergonomic risk factors of manual methods. Gen5 software offers advanced image analysis, and the LED filter cubes and objectives are easily and quickly changed according to user needs.
Lionheart LX is suited for a broad range of applications including slide scanning, cell population count and analysis, and intracellular detail analysis. For added convenience, a quick analyse feature provides instant cell count and confluence measurements from the live camera feed, prior to image capture.
46493pr@reply-direct.com Cell Culture Flask with Removable Microscope Slide Provides Superior Measurements for Fluorescence Applications
Clipmax is a 10cm2 tissue flask from TPP with a standard microscope slide (25mm x 75 mm) as a growing surface. It is intended for cell culture, staining, and immunofluorescence as it does not interfere with fluorescent labels-directly on the slide. It is also useful for viral and mycoplasma testing, chromosome studies toxicity tests and immune cytology. The growth area of the slide is opto-mechanically treated for an optimal cell adhesion and proliferation.
After the cell culture the medium chamber with the biocompatible seal ring can easily be detached from the slide. Cells may then be fixed, stained; cover slipped, and filed with the usual convenience and can be used directly for microscopic view. After removing the chamber of the Clipmax, the microscope slide with the cells can be fixed and stained directly on the microscope slide and can be used directly for immunocytochemistry and for various cell analyses. The transmission of the crystal-clear microscope slide is reported to be possible as of 250nm with a tailing at 280-300nm and stable between 350– 400nm until plus 750nm (+92% transmission within 400-800nm). The fluoroscopic measurements are better than with glass, PC, or PS and the protein absorption is less than using glass slides. The thermal
and optical features of the Clipmax slide are better than those made from PC, PET or TAC and in addition the slide is resistant to numerous chemicals such as Xylolite, alcohol, ether, (HCl, HNO3, H2SO4), (NaOH, NH4OH) or even H2O2. Also, biological coatings, i.g. with collagen, result in no loss of measuring signals. Finally, the handling of the Clipmax slide is much easier because there is no risk of injury, as it is plastic and not glass.
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