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Protect Your Work Zone with Horizontal Laminar Flow Cabinets
Air Science Purair Horizontal Laminar Flow Cabinets are a series of high-efficiency products designed to protect equipment and other contents of the work zone from particulates, for applications sensitive to such contamination.
This series is available in 2’, 3’, 4’, 5’, 6’ and 8’ widths in standard and extra tall heights for general applications.
Purair Laminar Flow Hoods are shipped fully assembled so no installation is required. The products are designed for desktop use, or may be installed on an optional mobile base stand.
The rear wall of vertical flow cabinets is perforated to reduce work surface turbulence by removing some of the airflow to the rear. Horizontal flow cabinets are designed with a lip on the rear of the work surface to protect the ULPA filter from spills. The high capacity air handling system delivers flow velocity of 0.35-0.45 m/s or 70-90 fpm. Customers may choose from a standard powder coated interior or stainless steel interior (-SS models). Purair Horizontal LF hoods have an ULPA filter pressure gauge to measure filter performance.
Accessories include an IV bar, service fixtures, base stand, UV lamp, and front door/cover.
42271pr@reply-direct.com Complete Cpf1-Based CRISPR Genome Editing System Available
Integrated DNA Technologies (IDT) is the first genomics company to develop and bring to market a complete ribonucleoprotein-based Cpf1 CRISPR system. The Alt-R™ A.s. Cpf1 CRISPR System inherits the optimised, efficient, and cost-effective traits of IDT’s innovative Cas9-based system while taking advantage of Cpf1’s natural AT-rich target sequence preference and ability to make staggered cuts. In addition, IDT is launching an associated range of CRISPR support tools to expand experimental options and capabilities for molecular biology researchers. The new tools extend the ease-of-use and
performance of IDT’s Alt-R system through options for fluorescent visualisation, enhanced nuclease transfection, and genome editing detection. Together, the new expanded Alt-R range breaks barriers to wider target spaces not
addressable by Cas9 systems alone, and provides a level of flexibility in experimental design not previously possible.
IDT’s Alt-R System already overcomes the limitations of using sgRNAs in the ribonucleoprotein (RNP) complex by enhancing editing efficiency and lowering toxicity. Now, in developing a complementary Cpf1-based system, IDT has opened up options for targeting AT-rich sequences. The new system includes the Alt-R A.s. Cpf1 nuclease, containing two integrated nuclear localisation sites, which complexes as an RNP with a minimal 41-44 nucleotide Alt-R CRISPR-Cpf1 crRNA. The system requires no tracrRNA, reducing potential reagent costs and experimental complexity.
The expanded range of Alt-R support tools now includes the Alt-R CRISPR-Cas9 tracrRNA—5’ ATTO™ 550, and Alt-R Electroporation Enhancers for Cas9 and Cpf1. The former allows in vivo fluorescent visualisation of the RNP complex and FACS enrichment of transfected cells without affecting RNP functionality, while the enhancers improve the efficiency of transfection using the Nucleofector (Lonza) and Neon (Thermo) electroporation systems. These new tools enable researchers to improve the overall efficiency of their genome editing over traditional methods. In addition, the new Alt-R Genome Editing Detection Kit provides a fast, easy, and low-cost method for confirming editing events with a T7 Endonuclease I (T7EI)-based mismatch detection system.
41952pr@reply-direct.com Research Products for Investigating Cellular Metabolism
Amsbio offers an extensive range of proteins, antibodies, assays and kits covering every single target of major cellular metabolic pathways including folate metabolism, pyruvate metabolism (with and without oxygen), citrate metabolism, O2 consumption and toxicity, oxidative stress and fatty acid oxygen measurement.
Cellular metabolism involves a series of interconnected biochemical reactions catalysed by enzymes inside a cell, better known as metabolic pathways. These reactions convert a substrate molecule or molecules through a series of metabolic intermediates, eventually yielding a final product. These processes allow organisms to grow and reproduce, maintain their structures, and respond to environmental changes.
Amsbio has assembled an unmatched collection of high quality, ready-to-use proteins and cell lysates for use in cell metabolism research. This includes a comprehensive range of compartmental total proteins specifically isolated from cell membrane, cytoplasma, cytoskeleton, nucleus and mitochondria. These focused cell lysates are available from human and many mammalian species / tissue types.
In addition, Amsbio offers cost effective, ready-to-use assays and ELISA kits offering high quality and quick detection of most of target proteins. Available for use with a wide range of sample types and species, these cutting edge kits use unique technologies to study various research areas including apoptosis, DNA damage, oxidative stress, angiogenesis, enzyme activity and cell migration.
41289pr@reply-direct.com
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