Ukraine National Academy of Science Wins DeNovix Pink Spectrophotometer / Fluorometer
DeNovix Inc is proud to announce the winner of a Special Edition Pink DS-11 FX+ Spectrophotometer/Fluorometer. The winner, randomly chosen from thousands of eligible entries to the company’s drawing, is Dr Olena Livinska of the National Academy of Science of Ukraine. Olena is a research associate in the Department of Physiology of Industrial Microorganisms in the Zabolotny Institute of Microbiology and Virology. Olena is also the Head of Council of Young Researchers (CYR) in the Institute.
Dr Livinska stated: “As a part of CYR I am especially happy to emphasise the importance of this prize for our young team of researchers. Our country is going through hard times with science funding decreased severely. Nevertheless, young researchers are still inspired and try to do their best. They continue their research and work as volunteers for the popularisation of science. I am proud to work with these people and feel grateful to DeNovix and Biolabtech for an opportunity to make my contribution.”
The DS-11 FX+, recently named Reviewers’ Choice Best Life Science Product 2017, is a stand-alone instrument for rapid UV-Vis and fluorometric quantification of biomolecules. The primary application
Dr Olena Livinska
is for quantification of 1uL samples of nucleic acids and proteins. Other applications include analysis of fluorescently labelled biomolecules, kinetic studies, and microbial cell quantification.
“Our team spoke with Olena the morning after she learned about being drawn as the winner. At DeNovix, we thought that the Pink FX+ was something unique that researchers would be excited about. But more than that, we hoped the winner would be a person who would really put the system to work. Olena was so thankful and excited. We know the instrument will expand the research abilities for her and the dozens of young scientists she’s working with in Kiev,” said Kevin Kelley,
Business Director at DeNovix.
Scientists around the world gained entries to the contest by visiting a DeNovix product page, watching videos, visiting the DeNovix Facebook page, sharing the contest with colleagues, etc.
Olena’s winning entry was generated from a visit to the DeNovix Facebook page.
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Harvesting Penicillin from Yeast Cells
“The rise of drug-resistant superbugs has brought a real urgency to our search for new antibiotics. Our experiments show that yeast can be engineered to produce a well-known antibiotic. This opens up the possibility of using yeast to explore the largely untapped treasure trove of compounds in the nonribosomal peptide family to develop a new generation of antibiotics and anti-inflammatories.”
Dr Tom Ellis Dr Ali Awan
Scientists from Imperial College London (ICL) have successfully inserted fungus genes into a yeast cell to make it produce penicillin molecules. In this early stage research* the synthetic biologists found that the re-engineered yeast, which manufactured the nonribosomal peptide antibiotic penicillin, displayed antibacterial properties against streptococcus bacteria when tested under laboratory conditions.
Dr Tom Ellis, from the Centre for Synthetic Biology at Imperial College London, explained: “Humans have been experimenting with yeast for thousands of years. From brewing beer to getting our bread to rise and more recently for making compounds like anti-malarial drugs, yeast is the microscopic workhorse behind many processes.
Dr Ali Awan, co-author from the Department of Bioengineering at Imperial College London, explained: “Fungi have had millions of years to evolve the capability to produce bacteria-killing penicillin. We scientists have only been working with yeast in this context for a handful of years, but now that we’ve developed the blueprint for coaxing yeast to make penicillin, we are confident we can further refine this method to create novel drugs in the future.
“We believe yeast could be the new mini-factories of the future, helping us to experiment with new compounds in the nonribosomal peptide family to develop drugs that counter antimicrobial resistance.”
The team are currently looking for fresh sources of funding and new industrial collaborators to take their research to the next level.
The research was carried out in conjunction with SynbiCITE, which is the UK’s national centre for the commercialisation of synthetic biology.
*Published in Nature Communications
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