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‘How to Build an Autoclave’ Video Launched
First 10-Colour, CE IVD Reagent for L&L Analysis Launched
Beckman Coulter Life Sciences further demonstrates its expertise in clinical flow cytometry with the launch of ClearLLab LS Lymphoid Screen Reagent,
Europe’s first CE-marked 10-colour, 12 antibody reagent combination for leukaemia and lymphoma analysis.
The ClearLLab LS Lymphoid Screen delivers greater confidence in results with a faster turnaround time. It eliminates 14 manual workflow steps, while streamlining five others; and is available through a dry unitised, ready to use formulation. ClearLLab has been specifically designed for the fast and accurate identification of haematolymphoid cell populations on the company’s Navios# flow cytometer.
Mario Koksch, Vice President and General Manager of Beckman Coulter’s Cytometry Business Unit said: “Beckman Coulter provides lab scientists with the tools they need to standardise and streamline workflow when using high content flow cytometry in clinical decision-making.”
British laboratory autoclave manufacturer Priorclave has just released a new How to Build an Autoclave video which takes the viewer on a journey through some of the key production, assembly and test procedures required for building an autoclave. It was filmed at the company’s UK manufacturing facility which produces some of the most advanced, energy-efficient, durable and reliable laboratory and research grade autoclave.
Each autoclave has three major parts; the pressure vessel, a frame and panels to support and enclose it plus wiring and controls.
The video starts where sheet and square-secation steel is off- loaded and held in the metals store to await call-off into the metal fabrication workshop ready to start the manufacturing process. The journey though production includes a visit to a specialist welding section where that key component, the stainless-steel pressure, is manufactured. It is shown being creating using a unique seam welder developed by Priorclave so that they can produce ultra-smooth joins.
In the assembly area door and closure fittings are added to the pressure vessel so that it can be made water-tight ready for pressure testing. The final part of the video moves to the test centre where the autoclave is run; is function and safety tested against an extended checklist before being packed ready for despatch.
As a specialist in the design and manufacture of laboratory autoclaves Priorclave delivers its autoclaves around the world, each produced to satisfy individual customer demands in terms of functionality, operating environment and special installation requirements.
For those interested in how these first-class are built the video can be viewed at
https://youtu.be/TFp2jBjD__c.
As a successful laboratory autoclave manufacturer Priorclave has developed more than 60 standards models which feature in its current range of benchtop, top and front loading, as well as double-door and power-door autoclaves. The company has also created an extensive range of ‘options and accessories to ensure that it can provide a perfect match to meet the customer sterilising requirements.
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Dr Kosch explained: “If survival rates are to be improved, we need to be able to diagnose life- threatening haematolymphoid diseases as quickly as possible. With ClearLLab LS Lymphoid Screen, the lab now has the means to speed up the delivery of patient results to clinicians, while having added confidence in their accuracy.”
The ClearLLab LS Lymphoid Screen is the first of an advanced range of Beckman Coulter clinical flow cytometry products which will cater to different global workflow requirements over the next five years. It is compatible with the World Health Organization (WHO) 2008-revised classification of myeloid neoplasms and acute leukemia. WHO, in collaboration with the European Association for Haematopathology and the Society for Haematopathology, made important changes to the classification of these diseases, including new criteria for the recognition of some previously described neoplasms as well as clarification and refinement of the defining criteria for others.
The Navios delivers increased accuracy and resolution even for dim stains and quantitation, able to maintain a high yield of processed signals, more than 90%, even at 25,000 events per second. The instrument incorporates 12 detectors which include 10 fluorescence detectors and two light scattering detectors. Simultaneous measurements of integral, peak and width are available for all scatter measurements and up to 10 fluorescent parameters.
The ClearLLab product line also includes five panels of pre-mixed cocktails in liquid format for those customers carrying out flow cytometry characterisation of hematolymphoid neoplasia on Beckman Coulter’s FC 500 instrument.
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Guide to Safe Use of Laboratory Heating Blocks
Asynt announces an updated version of its best practice guide developed to enable laboratory personnel to more safely use heating block systems.
Written in conjunction with the Department of Chemistry, University of St Andrews (UK) and Advanced Chemical Safety Inc (USA) the illustrated guide leads you through best practices for glassware inspection, setting up your reaction, heating your reaction and the post-reaction cool down phase.
Popular in labs worldwide, when used properly, heating blocks provide a safe, convenient and productive tool for heating round bottomed flasks, tubes and vials. Used in combination with a standard hotplate stirrer, heating blocks are proven to provide superior heat-conducting properties compared to oil baths. They also pose a far lower fire risk and their use makes the clean-up of glassware far easier as there is no residual oil contamination on the outside of the reaction vessel. In addition to accelerating your chemical reactions, heating blocks ensure a safer, cleaner, healthier working environment.
For a copy of the best practice guide please visit
http://www.asynt.com/services/best-practice/ 41164pr@reply-direct.com
Automated System Helps Veterinary Pharmaceutical Company Rapidly Generate Accurate Data on Antibiotic Potency
Synbiosis is pleased to announce its ProcScan inhibition zone measurement system is being used together with its SynStats statistical analysis software at specialist Dutch veterinary pharmaceutical firm, Produlab Pharma to accurately and reproducibly assess the quality of veterinary antibiotics.
Microbiologists at Produlab Pharma are using the ProcScan automated system to generate images of inhibition zones around antibiotics on large (240 mm x 240 mm) antibiotic susceptibility testing plates. The images are scanned directly into software, which automatically measures zone sizes and these values are transferred into SynStats statistical software. This rapidly analyses the results to provide standard curve and potency data. Using ProcScan in combination with SynStats is helping microbiologists at Produlab Pharma to precisely assess the efficacy of existing and re-engineered antibiotics to treat diseases such as mastitis in cattle.
Dave van Reusel, Microbiologist at Produlab Pharma commented: “We used to measure inhibition zones manually with callipers and then record the results on the computer. It would take us 30 minutes to analyse one plate and after this we had no image of our plates to refer to so there was no proof of our results to look at later.”
Dave added: “We chose the ProcScan because it is the only system that can image large antibiotic susceptibility testing plates and measure inhibition zones in a 6 x 6 grid. Before we had the ProcScan, it would require hours to analyse a run of 20-30 assay plates, now it takes a fraction of the time and we can record raw plate images to provide evidence for clients or regulators to assess when they need to.”
“Data integrity is currently a hot issue across the pharmaceutical industry,” stated Kate George, Senior Divisional Manager at Synbiosis, “scientists at Produlab Pharma are demonstrating that ProcScan and SynStats is a must have combination for quality assurance laboratories where generating accurate, consistent and more importantly, archived raw and analysed data of any antibiotics’ potency are critical requirements.”
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INTERNATIONAL LABMATE - JANUARY/FEBRUARY 2017
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