Extended-Release Injectable Parasiticide 5% Sterile Solution NADA 141-327, Approved by FDA for subcutaneous injection For the Treatment and Control of Internal and External Parasites of Cattle on Pasture with Persistent Effectiveness
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
INDICATIONS FOR USE LONGRANGE, when administered at the recommended dose volume of 1 mL per 110 lb (50 kg) body weight, is effective in the treatment and control of 20 species and stages of internal and external parasites of cattle:
Gastrointestinal Roundworms Bunostomum phlebotomum – Adults and L4
Cooperia oncophora – Adults and L4 Cooperia punctata – Adults and L4 Cooperia surnabada – Adults and L4 Haemonchus placei – Adults
Oesophagostomum radiatum – Adults
Ostertagia lyrata – Adults Ostertagia ostertagi – Adults, L4 Trichostrongylus axei – Adults and L4
, and inhibited L4 Mites
Trichostrongylus colubriformis – Adults Parasites
Gastrointestinal Roundworms Bunostomum phlebotomum Cooperia oncophora Cooperia punctata Haemonchus placei
Oesophagostomum radiatum Ostertagia lyrata
Ostertagia ostertagi Trichostrongylus axei
Lungworms Dictyocaulus viviparus
Persistent Effectiveness
150 days 100 days 100 days 120 days 120 days 120 days 120 days 100 days
150 days
DOSAGE AND ADMINISTRATION LONGRANGE® (eprinomectin) should be given only by subcutaneous injection in front of the shoulder at the recommended dosage level of 1 mg eprinomectin per kg body weight (1 mL per 110 lb body weight).
WARNINGS AND PRECAUTIONS Withdrawal Periods and Residue Warnings
Animals intended for human consumption must not be slaughtered within 48 days of the last treatment. This drug product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. A withdrawal period has not been established for pre-ruminating calves. Do not use in calves to be processed for veal.
Animal Safety Warnings and Precautions The product is likely to cause tissue damage at the site of injection, including possible granulomas and necrosis. These reactions have disappeared without treatment. Local tissue reaction may result in trim loss of edible tissue at slaughter. Observe cattle for injection site reactions. If injection site reactions are suspected, consult your veterinarian. This product is not for intravenous or intramuscular use. Protect product from light. LONGRANGE® (eprinomectin) has been developed specifically for use in cattle only. This product should not be used in other animal species.
When to Treat Cattle with Grubs LONGRANGE effectively controls all stages of cattle grubs. However, proper timing of treatment is important. For the most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season.
Environmental Hazards Not for use in cattle managed in feedlots or under intensive rotational grazing because the environmental impact has not been evaluated for these scenarios.
Other Warnings: Underdosing and/or subtherapeutic concentrations of extended- release anthelmintic products may encourage the development of parasite resistance. It is recommended that parasite resistance be monitored following the use of any anthelmintic with the use of a fecal egg count reduction test program.
TARGET ANIMAL SAFETY Clinical studies have demonstrated the wide margin of safety of LONGRANGE® (eprinomectin). Overdosing at 3 to 5 times the recommended dose resulted in a statistically significant reduction in average weight gain when compared to the group tested at label dose. Treatment-related lesions observed in most cattle administered the product included swelling, hyperemia, or necrosis in the subcutaneous tissue of the skin. The administration of LONGRANGE at 3 times the recommended therapeutic dose had no adverse reproductive effects on beef cows at all stages of breeding or pregnancy or on their calves. Not for use in bulls, as reproductive safety testing has not been conducted in males intended for breeding or actively breeding. Not for use in calves less than 3 months of age because safety testing has not been conducted in calves less than 3 months of age.
STORAGE Store at 77° F (25° C) with excursions between 59° and 86° F (15° and 30° C). Protect from light.
Made in Canada. Manufactured for Merial Limited, Duluth, GA, USA. ®LONGRANGE and the Cattle Head Logo are registered trademarks of Merial. ©2013 Merial. All rights reserved. 1050-2889-02, Rev. 05/2012
®JOHN DEERE is a registered trademark, and ™GATOR is a trademark, of Deere & Company. Deere & Company neither sponsors nor endorses this promotion.
®LONGRANGE and the Cattle Head Logo are registered trademarks of Merial. All other marks are the property of their respective owners. ©2014 Merial Inc., Duluth, GA. All rights reserved. RUMIELR1455-A (08/14)
tscra.org Watch for a chance to win a JOHN DEERE®
Scan to watch video and enter, or go to
theLONGRANGElook.com/cc43.
GATOR™
IMPORTANT SAFETY INFORMATION: Do not treat within 48 days of slaughter. Not for use in female dairy cattle 20 months of age or older, including dry dairy cows, or in veal calves. Post- injection site damage (e.g., granulomas, necrosis) can occur. These reactions have disappeared without treatment.
1
Available in 500 mL, 250 mL and 50 mL bottles. Administer subcutaneously at 1 mL/110 lbs.
Dependent upon parasite species, as referenced in FOI summary and LONGRANGE product label.
2 LONGRANGE product label. 3 Data on file at Merial.
February 2015 The Cattleman 15
Sarcoptes scabiei var. bovis Durations of
Lungworms
Dictyocaulus viviparus – Adults
Grubs Hypoderma bovis
A deworming with LONGRANGE®
THE WEIGHT GAIN IS REAL. Go ahead, blink.
can help keep parasites from eating into your profits.
(eprinomectin)
If you used a conventional dewormer like CYDECTIN® (moxidectin), SAFE-GUARD® (fenbendazole) or in combination, your cattle
are probably already reinfected with parasites. Tat’s because conventional dewormers only last 14 to 42 days and SAFE-GUARD has no persistent effect. Only LONGRANGE delivers up to 100 to 150 days of parasite control in a single treatment.1,2
When you look at the benefits of season-long parasite control with LONGRANGE – you’ll see you have a lot to gain.
Use LONGRANGE on your cow/calf operation and ee the difference for yourself.
much as
As
Over cattle treated with CYDECTIN + SAFE-GUARD. Talk to your veterinarian or visit
theLONGRANGElook.com
40 LBS 3
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