search.noResults

search.searching

dataCollection.invalidEmail
note.createNoteMessage

search.noResults

search.searching

orderForm.title

orderForm.productCode
orderForm.description
orderForm.quantity
orderForm.itemPrice
orderForm.price
orderForm.totalPrice
orderForm.deliveryDetails.billingAddress
orderForm.deliveryDetails.deliveryAddress
orderForm.noItems
CASE STUDIES


BES completes £50m upgrade W


BES has completed a £50 million project to upgrade and future- fit the warehousing, packing and logistics facilities at AstraZeneca’s Macclesfield site.


orking collaboratively with AstraZeneca as an integral part of the company’s user, quality assurance and


project management team, BES was principal designer and principal contractor on the three- phase programme. The project involved full design, construction and commissioning of a new high bay warehouse, a low bay warehouse refurbishment and a technically-demanding Global Packing Centre. Co-ordinated to enable business-as-usual operations for AstraZeneca and delivered in compliance with Good Manufacturing Practice (GMP) standards, the project was carried out over a four-year period and involved more than one million man-hours. BES’ multi-disciplinary team worked closely with the client to co-ordinate all construction work and upgrades to mechanical and electrical services to prevent any risk of business interruption. The company also implemented a range of SHE initiatives, resulting in an excellent safety record throughout the project and an award from AstraZeneca for management of health and safety. The new high bay warehouse was designed by BES as a fully-automated storage facility to


enable increased pharmaceutical stock holding and capacity for future expansion. The 18,000 metres squared, 30 metres high very narrow aisle (VNA) facility incorporates complex air handling engineering to maintain mission-critical temperature and relative humidity parameters and ensure consistent airflow for all racking throughout the building. BES also incorporated a hypoxic fire suppression system into the mechanical services to reduce fire risk and protect stored goods from fire suppressants.


The low bay warehouse refurbishment required careful sequencing of construction works by the BES team to enable operational continuity for AstraZeneca while a section of the existing facility was refurbished. This included adaptations to service routes, which were mapped in a Revit model to ensure effective co-ordination. Dedicated HVAC services were installed and commissioned for each warehouse area without disruption to the client’s critical activities.


For the final phase, BES designed and delivered a global packing centre, comprising nine grade D packing cells adjoining a common secondary packing space, along with wash bay,


tool store and associated office accommodation. Stringent air pressure regimes were engineered into the facility to restrict microbial and particulate contamination within compliant limits, with air locks employed to eliminate cross-contamination. BES also designed, installed and commissioned a complex HVAC system using primary and secondary air handling units, along with modularised service distribution units, to deliver a temperature, humidity and pressure-controlled environment for each area. The finished project provides a storage,


packing and logistics infrastructure to support future growth at AstraZeneca’s Macclesfield site. Christine Haigh, senior engineering project manager, AstraZeneca, commented: “This has been an extremely challenging project and by working in partnership with BES we have delivered a modern, forward- looking warehousing and packing facility to programme and cost with no unplanned business interruption and an excellent safety performance. For now, and the foreseeable future, this facility will benefit patients all over the world who depend on AstraZeneca’s life- changing medicines.”


www.acr-news.com


February 2020 45


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46  |  Page 47  |  Page 48  |  Page 49  |  Page 50  |  Page 51  |  Page 52  |  Page 53  |  Page 54  |  Page 55  |  Page 56  |  Page 57  |  Page 58  |  Page 59  |  Page 60  |  Page 61  |  Page 62  |  Page 63  |  Page 64  |  Page 65  |  Page 66  |  Page 67  |  Page 68  |  Page 69  |  Page 70  |  Page 71  |  Page 72  |  Page 73  |  Page 74  |  Page 75  |  Page 76