Perspective Patel, Cole, Bradshaw et al.
8 Trim PJ, Francese S, Clench MR. Imaging mass spectrometry for the assessment of drugs and metabolites in tissue. Bioanalysis 1(2), 309–319 (2009).
9 Gessel MM, Norris JL, Caprioli RM. MALDI imaging mass spectrometry: spatial molecular analysis to enable a new age of discovery. J. Proteomics 107, 71–82 (2014).
10 Trim PJ, Djidja MC, Muharib T et al. Instrumentation and software for mass spectrometry imaging‐‐making the most of what you’ve got. J. Proteomics. 75(16), 4931–4940 (2012).
11 Ellis SR, Brown SH, In Het Panhuis M, Blanksby SJ, Mitchell TW. Surface analysis of lipids by mass spectrometry: more than just imaging. Prog. Lipid Res. 52(4), 329–353 (2013).
12 Kafka AP, Kleffmann T, Rades T, McDowell A. The application of MALDI TOF MS in biopharmaceutical research. Int. J. Pharm. 417(1–2), 70–82 (2011).
13 Troendle FJ, Reddick CD, Yost RA. Detection of pharmaceutical compounds in tissue by matrix-assisted laser desorption/ionization and laser desorption/chemical ionization tandem mass spectrometry with a quadrupole ion trap. J. Am. Soc. Mass Spectrom. 10(12), 1315–1321 (1999).
14 Reyzer ML, Hsieh Y, Ng K, Korfmacher WA, Caprioli RM. Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry. J. Mass Spectrom. 38(10), 1081–1092 (2003).
15 Stoeckli M, Staab D, Schweitzer A. Compound and metabolite distribution measured by MALDI mass spectrometric imaging in whole-body tissue sections. Int. J. Mass Spectrom. 260(2–3), 195–202 (2007).
16 Khatib-Shahidi S, Andersson M, Herman JL, Gillespie TA, Caprioli RM. Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry. Anal. Chem. 78(18), 6448–6456 (2006).
17 Fournier I, Wisztorski M, Salzet M. Tissue imaging using MALDI-MS: a new frontier of histopathology proteomics. Expert Rev. Proteomics 5(3), 413–424 (2008).
18 Groseclose MR, Andersson M, Hardesty WM, Caprioli RM. Identification of proteins directly from tissue: in situ tryptic digestions coupled with imaging mass spectrometry. J. Mass Spectrom. 42(2), 254–262 (2007).
19 Shimma S, Furuta M, Ichimura K, Yoshida Y, Setou M. A novel approach to in situ proteome analysis using chemical inkjet printing technology and MALDI-QIT-TOF tandem mass spectrometer. J. Mass Spectrom. Soc. Jpn 54(4), 133–140 (2006).
20 Lemaire R, Desmons A, Tabet JC, Day R, Salzet M, Fournier I. Direct analysis and MALDI imaging of formalin-fixed, paraffin-embedded tissue sections. J. Proteome Res. 6(4), 1295–1305 (2007).
21 Schwamborn K. Imaging mass spectrometry in biomarker discovery and validation. J. Proteomics 75(16), 4990–4998 (2012).
22 Prideaux B, Stoeckli M. Mass spectrometry imaging for drug distribution studies. J. Proteomics 75(16), 4999–5013 (2012).
23 Nilsson A, Fehniger TE, Gustavsson L et al. Fine mapping the spatial distribution and concentration of unlabeled drugs within tissue micro-compartments using imaging mass spectrometry. PLoS ONE 5(7), e11411 (2010).
24 Marko-Varga G, Végvári A, Rezeli M et al. Understanding drug uptake and binding within targeted disease micro- environments in patients: a new tool for translational medicine. Clin. Transl. Med. 1(1), 8–9 (2012).
25 Cole LM, Djidja MC, Bluff J et al. Investigation of protein induction in tumour vascular targeted strategies by MALDI MSI. Methods 54(4), 442–453 (2011).
26 Atkinson SJ, Loadman PM, Sutton C, Patterson LH, Clench MR. Examination of the distribution of the bioreductive drug AQ4N and its active metabolite AQ4 in solid tumours by imaging matrix-assisted laser desorption/ionisation mass spectrometry. Rapid Commun. Mass Spectrom. 21(7), 1271–1276 (2007).
27 van Kampen JJ, Burgers PC, de Groot R, Gruters RA, Luider TM. Biomedical application of MALDI mass spectrometry for small-molecule analysis. Mass Spectrom. Rev. 30(1), 101–120 (2011).
28 Munteanu B, Meyer B, von Reitzenstein C et al. Label- free in situ monitoring of histone deacetylase drug target engagement by matrix-assisted laser desorption ionization-mass spectrometry biotyping and imaging. Anal. Chem. 86(10), 4642–4647 (2014).
•• The monitoring of drug-induced mass shifts in protein ion fingerprints/images directly corresponding to histone post- transcriptional modifications is a novel pharmacodynamic approach for analyzing engagement of drug targets and intact cell responses via MALDI-MS.
29 Djidja MC, Claude E, Snel MF et al. Novel molecular tumour classification using MALDI-mass spectrometry imaging of tissue micro-array. Anal. Bioanal. Chem. 397(2), 587–601 (2010).
• Potentially a high-throughput method for the classification and interrogation of pancreatic cancer tissue by analyzing formalin-fixed paraffin-embedded tissue microarrays. This would be advantages in a clinical setting.
30 Demichelis F, Magni P, Piergiorgi P, Rubin MA, Bellazzi R. A hierarchical Naive Bayes Model for handling sample heterogeneity in classification problems: an application to tissue microarrays. BMC Bioinformatics 7, 514 (2006).
31 Battifora H, Mehta P. The checkerboard tissue block. An improved multitissue control block. Lab. Invest. 63(5), 722–724 (1990).
32 Kononen J, Bubendorf L, Kallioniemi A et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat. Med. 4(7), 844–847 (1998).
33 Abd El-Rehim DM, Ball G, Pinder SE et al. High- throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses. Int. J. Cancer 116(3), 340–350 (2005).
34 Djidja MC, Francese S, Claude E et al. Targeting of hypoxia in AQ4N-treated tumour xenografts by MALDI-ion mobility separation–mass spectrometry imaging. Curr. Anal. Chem. (9), 212–225 (2013).
35 Cole LM, Bluff JE, Carolan VA, Paley MN, Tozer GM, Clench MR. MALDI-MSI and label-free LC-ESI-MS/
100
Bioanalysis (2015) 7(1)
future science group
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76 |
Page 77 |
Page 78 |
Page 79 |
Page 80 |
Page 81 |
Page 82 |
Page 83 |
Page 84 |
Page 85 |
Page 86 |
Page 87 |
Page 88 |
Page 89 |
Page 90 |
Page 91 |
Page 92 |
Page 93 |
Page 94 |
Page 95 |
Page 96 |
Page 97 |
Page 98 |
Page 99 |
Page 100 |
Page 101 |
Page 102 |
Page 103 |
Page 104 |
Page 105 |
Page 106 |
Page 107 |
Page 108 |
Page 109 |
Page 110 |
Page 111 |
Page 112 |
Page 113 |
Page 114 |
Page 115 |
Page 116 |
Page 117 |
Page 118 |
Page 119 |
Page 120 |
Page 121 |
Page 122 |
Page 123 |
Page 124 |
Page 125 |
Page 126 |
Page 127 |
Page 128 |
Page 129 |
Page 130 |
Page 131 |
Page 132 |
Page 133 |
Page 134 |
Page 135 |
Page 136 |
Page 137 |
Page 138 |
Page 139 |
Page 140 |
Page 141 |
Page 142 |
Page 143 |
Page 144 |
Page 145 |
Page 146 |
Page 147 |
Page 148 |
Page 149 |
Page 150 |
Page 151 |
Page 152 |
Page 153 |
Page 154