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RAPIDARC®


Article provided by Varian Medical Systems


A


t a recent clinical symposium held earlier this year during the annual conference of the


European Society for Therapeutic Radiology and Oncology (ESTRO) in London, European cancer experts reported on how they have been able to treat many forms of cancer, including liver and lung cancer, with high dose radiosurgery by using RapidArc technology from Varian Medical Systems. In front of an audience of more than 500 oncology professionals, clinicians from leading cancer centers in Italy and the Netherlands gave detailed accounts of pioneering SBRT treatments at their centers. SBRT is a form of radiosurgery for tumors in the body. Dr. Marta Scorsetti, head of radiation


oncology at the Humanitas Clinic in Milan, described an ongoing study assessing the safety and feasibility of using RapidArc to SBRT in the treatment of liver metastases. Results, after seven months, were a local tumor control rate of nearly 94%. “There is undoubtedly a great need


for improved therapies for liver cancers that cannot be treated surgically,” said Dr. Scorsetti. “SBRT offers the possibility of a non-invasive treatment, delivered in just a few treatment sessions.” Professor Ben Slotman, head of radiation oncology at VU University Medical Center in Amsterdam, presented data from his hospital’s lung cancer


«There is undoubtedly a great need for improved therapies for liver cancers that cannot be treated surgically»


26 www.lifesciencesmagazines.com


program. Clinicians there had treated more than 800 stage 1 lung tumor patients in the last eight years. Since 2008, all lung SBRT treatments


at VU have been delivered using RapidArc technology, many on Varian’s TrueBeam™


Slotman, the main benefit of RapidArc for lung patients is the shorter treatment time, which means less risk of motion during treatment. “This is especially important for SBRT, where high doses are delivered over fewer treatment sessions,” he says. “The delivery of the highest dose for lung tumors was reduced from 30 minutes to just six minutes. By using the TrueBeam system’s High Intensity Mode in the very near future, we expect to reduce the treatment time to less than three minutes.”


RAPIDARC RapidArc technology delivers an image- guided, intensity- modulated treatment with one or more arcs of the treatment machine around the patient. During a treatment, the RapidArc software varies three parameters simultaneously - the shape of the treatment beam, the dose delivery rate, and the speed of rotation - to accurately dose the tumor while minimizing exposure of surrounding healthy tissues. Many RapidArc treatments can be


system. According to Prof.


completed with just one rotation of the machine; some of the more complex treatments require multiple rotations. For complex or for radiosurgical treatments, RapidArc can be delivered in multiple arcs, or with couch rotations for reaching tumors from many different angles. Since it was introduced in 2007, over 1,000 RapidArc radiotherapy-enabled systems have been installed at hospitals and clinics around the world. ■


AH Image © RapidArc®


RADIOTHERAPY:


DELIVERING NON-INVASIVE RADIO-SURGERY PROCEDURES FOR LUNG AND LIVER CANCER


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