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research round-up
EFFECT OF ANTIOXIDANT TREATMENT ON THE SHEAR BOND STRENGTH OF COMPOSITE RESIN TO BLEACHED ENAMEL
Kunt GE, Yilmaz N, Şen S, Dede DÖ. Acta Odontol Scand 2011; 69(5): 287–91
strength of composite resin to enamel after bleaching with two different bleaching systems. Materials and methods: seventy flat enamel surfaces were prepared from freshly extracted human molars using a low speed diamond saw. Then the specimens were divided into seven random groups (n = 10) to apply different procedures; namely, bleaching with White smile and bonding with composite resin (G1), bleaching with White smile, treatment with ascorbic acid and bonding with composite resin (G2), bleaching with White smile, immersing in artificial saliva for 2 weeks and
T his sTudy examined The antioxidant treatment on the shear bond
bonding with composite resin (G3), bleaching with Opalesence and bonding with composite resin (G4), bleaching with Opalesence, treatment with ascorbic acid and bonding with composite resin (G5) and bleaching with Opalesence, immersing in artificial saliva for 2 weeks and bonding with composite resin (G6). another group was used as a control group. shear bond test was performed on all specimens and data were analyzed using one way anOVa and Bonferroni’s test (P < 0.05). Results: Bond strengths of bleached specimens were significantly lower than those of non- bleached specimens. no statistical difference was found in bond strength between the bleached and non-bleached groups when the antioxidant treatment was carried out. Conclusion: Ten per cent ascorbic acid treatment was found to be an effective method to reverse the compromised bond strength.
TUMOR NECROSIS FACTOR-α IN VITILIGO: DIRECT CORRELATION BETWEEN TISSUE LEVELS AND CLINICAL PARAMETERS
Kim NH, Torchia D, Rouhani P, Roberts B, Romanelli P. Cutan Ocul Toxicol 2011; 30(3): 225–7
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may play a role in the pathogenesis of nonsegmental vitiligo, and successful cases of vitiligo treated with TnF-α inhibitors have been recently reported. Materials and methods: Two cases of refractory generalized vitiligo, which showed high tissue levels of TnF-α, were commenced anti-TnF-α antibody etanercept 50 mg weekly. a retrospective study, considering chart review and
e October 2011 |
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xperimenTal eVidences haVe shown that tumor necrosis factor (TnF)-α
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immunohistochemical staining for TnF-α, was then carried out on eight additional patients affected by untreated vitiligo. Results: etanercept achieved improvement of vitiligo in two patients at 6-month follow-up. Five out of eight specimens showed a strong cytoplasmic staining for TnF-α. considering all 10 cases, patients with a strong TnF-α staining were characterized by a higher vitiligo disease activity score than patients with a weak staining. Discussion: These findings, albeit limited in significance by the low number of cases and the retrospective nature of the study, confirm a probable role of TnF-α in the pathogenesis of vitiligo. The intensity of TnF-α staining in vitiligo lesions may be worth to be further studied as a biomarker for potentially successful anti-TnF-α treatment of nonsegmental vitiligo in cases refractory to conventional treatment.
COMPARISON OF HAIR REDUCTION WITH THREE LASERS AND LIGHT SOURCES: PROSPECTIVE, BLINDED AND CONTROLLED STUDY
Sochor M, Curkova AK, Schwarczova Z, Sochorova R, Simaljakova M, Buchvald J. Cosmet Laser Ther 2011; 13(5): 210–5
methods: intense pulsed light (ipl), a combination of ipl and radio frequency (rF) and diode laser (810 nm). Methods: Forty participants were treated within three standardized squares on lateral sites on their legs. each of these squares was treated twice with an interval of 4–6 weeks. The fourth square was left as a control. a blinded
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he main GOal OF This sTudy Was TO compare the hair removal efficacy of three
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